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Scholar Results 1 - 6 of 6 citing McDuffie: Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase.... (0.08 sec) 

Cardiac 12/15 lipoxygenase-induced inflammation is involved in heart failure

- slas.ac.cn [PDF] 
Y Kayama, T Minamino, H Toko, M Sakamoto, I … - Journal of Experimental …, 2009 - jem.rupress.org
To identify a novel target for the treatment of heart failure, we examined gene expression in the
failing heart. Among the genes analyzed, Alox15 encoding the protein 12/15 lipoxygenase (LOX) was
markedly up-regulated in heart ...
Related articles - All 4 versions

[PDF] Parsing the Supporting Genetic Data


SP Weisberg, RL Leibel - DIABETES, 2008 - Am Diabetes Assoc
P rogenitors of the nonobese diabetic mouse strain (NOD/Shi) arose spontaneously in a colony at the
Shionogi Research Laboratories in Aburahi, Ja- pan in the 1970s. The strain has been used
extensively in efforts to elucidate ...
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Cardiac 12/15 lipoxygenase–induced inflammation is involved in heart failure


I Shimizu, H Takahashi, S Okada, K Tateno, J … - Journal of Experimental … - jem.rupress.org
Heart failure is a clinical syndrome that is as- sociated with various cardiovascular diseases such
as hypertension and myocardial infarction (Libby and Braunwald, 2008). Comprehensive management
using current therapeutic options ...
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An Apparent Role for Alox15 in the Pathogenesis of Diabetes in the NOD Mouse

- diabetesjournals.org
SP Weisberg, RL Leibel - Diabetes, 2008 - Am Diabetes Assoc
Progenitors of the nonobese diabetic mouse strain (NOD/Shi) arose spontaneously in a colony at the
Shionogi Research Laboratories in Aburahi, Japan in the 1970s. The strain has been used extensively
in efforts to elucidate the ...
Related articles - BL Direct - All 3 versions

12/15-Lipoxygenase Is Required for the Early Onset of High Fat Diet-Induced …


DD Sears, PD Miles, J Chapman, JM Ofrecio, F … - 2009 - pubmedcentral.nih.gov
Cells over-expressing 12/15LO secreted two potent chemokines, MCP-1 and osteopontin, implicated in
the development of insulin resistance. We assessed adipose tissue inflammation and whole body
insulin resistance in wild type ...
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Differential Transcriptional Expression of PPARα, PPARγ1, and PPARγ2 in the …


NS Yaacob, MA Kaderi, MN Norazmi - Journal of Clinical Immunology, 2009 - Springer
Abstract Background The peroxisome proliferator-activated recep- tors (PPARs) have been implicated
in immune regulation. We determined the transcriptional expression of the three isoforms, PPARα,
PPARγ1, and PPARγ2 in the ...
Related articles - All 2 versions


 


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