B Skinningsrud, ES Husebye, K Gervin, K … - European Journal of Human Genetics, 2008 - nature.com The tyrosine-protein phosphatase non-receptor type 22 (PTPN22) gene was recently
identified as an important genetic susceptibility factor in several autoimmune
diseases. The increased risk has been broadly explained by the 1858T-allele ... Cited by 15 - Related articles - All 3 versions
- ►endojournals.org A Huber, F Menconi, S Corathers, EM … - Endocrine Reviews, 2008 - Endocrine Soc Type 1 diabetes (T1D) and autoimmune thyroid diseases (AITD) frequently occur
together within families and in the same individual. The co-occurrence of T1D
and AITD in the same patient is one of the variants of the autoimmune ... Cited by 11 - Related articles - All 4 versions
- ►nih.gov EE Baschal, GS Eisenbarth - Journal of autoimmunity, 2008 - Elsevier A series of genes and loci influencing the genetic risk of type 1A
(immune-mediated) diabetes are now well characterized. These include genes of
the major histocompatibility complex (MHC), polymorphisms 5′ of the ... Cited by 13 - Related articles - All 3 versions
M Zoledziewska, G Costa, M Pitzalis, E Cocco, … - Genes and Immunity, 2008 - nature.com Variation within intron 19 of the CLEC16A (KIAA0350) gene region was recently
found to be unequivocally associated with type 1 diabetes (T1D) in genome-wide
association (GWA) studies in Northern European populations. A variant in ... Cited by 12 - Related articles - All 3 versions
S Liu, H Wang, Y Jin, R Podolsky, MV Reddy, … - Human Molecular Genetics, 2009 - Oxford Univ Press Genome-wide association (GWA) studies revealed a number of single nucleotide
polymorphisms (SNPs) significantly associated with type 1 diabetes (T1D). In an
attempt to confirm some of these candidate associations, we genotyped 2046 ... Cited by 7 - Related articles - All 3 versions
D Contu, L Morelli, F Santoni, JW Foster, P … - Plos One, 2008 - pubmedcentral.nih.gov Conceived and designed the experiments: FC LM DC FS PF. Performed the
experiments: LM DC. Analyzed the data: FC LM DC FS. Contributed
reagents/materials/analysis tools: FC. Wrote the paper: FC. Other: Designed ... Cited by 6 - Related articles - All 5 versions
V Orru, SJ Tsai, B Rueda, E Fiorillo, SM … - Human Molecular Genetics, 2009 - Oxford Univ Press PTPN22 encodes the protein tyrosine phosphatase (PTP) LYP, which is a critical
gatekeeper of T-cell receptor (TCR) signaling. In T-cells, LYP (lymphoid
tyrosine phosphatase) potently inhibits signaling through dephosphorylation ... Cited by 4 - Related articles - All 3 versions
D Contu, L Morelli, F Santoni, JW Foster, P …, 2008 - eprints.uniss.it The island of Sardinia shows a unique high incidence of several autoimmune
diseases with multifactorial inheritance, particularly type 1 diabetes and
multiple sclerosis. The prior knowledge of the genetic structure of this ... Related articles - View as HTML - All 2 versions