- ►nih.gov MCY Ng, KS Park, B Oh, CHT Tam, YM Cho, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— We confirmed the associations of TCF7L2, SLC30A8, HHEX, CDKAL1,
CDKN2A/CDKN2B, IGF2BP2, and FTO with risk for type 2 diabetes, with odds ratios
ranging from 1.13 to 1.35 (1.3 × 10 −12 < P unadjusted < 0.016). In ... Cited by 51 - Related articles - All 4 versions
- ►diabetesjournals.org [PDF] RM Freathy, NJ Timpson, DA Lawlor, A Pouta, … - Diabetes, 2008 - Am Diabetes Assoc Page 1. Common variation in the FTO gene alters diabetes-related metabolic
traits to the extent expected, given its effect on BMI ... Cited by 40 - Related articles - BL Direct - All 3 versions
- ►physiology.org G Stratigopoulos, SL Padilla, CA LeDuc, E … - … Journal of Physiology- Regulatory, Integrative and …, 2008 - Am Physiological Soc Two recent, large whole-genome association studies (GWAS) in European
populations have associated a 47-kb region that contains part of the FTO gene
with high body mass index (BMI). The functions of FTO and adjacent FTM in ... Cited by 41 - Related articles - BL Direct - All 3 versions
- ►angrylapdog.com JE Cecil, R Tavendale, P Watt, MM … - The New England Journal of Medicine, 2008 - content.nejm.org.p.angrylapdog.com Results In the total study group and the subsample, the A allele of rs9939609
was associated with increased weight (P=0.003 and P=0.049, respectively) and
body-mass index (P=0.003 and P=0.03, respectively). In the intensively ... Cited by 33 - Related articles - Cached - All 5 versions
- ►nih.gov K Hotta, Y Nakata, T Matsuo, S Kamohara, K … - Journal of human genetics, 2008 - Springer Abstract Variations in the fat-mass and obesity-associated gene (FTO) are
associated with the obesity phenotype in many Caucasian populations. This
association with the obesity phenotype is not clear in the Japanese. To ... Cited by 29 - Related articles - BL Direct - All 7 versions
RJ Loos, C Bouchard - Obesity Reviews, 2008 - interscience.wiley.com Genome-wide association, the latest gene-finding strategy, has led to the first
major success in the field of obesity genetics with the discovery of FTO (fat
mass and obesity associated gene) as an obesity–susceptibility gene. A ... Cited by 24 - Related articles - BL Direct - All 4 versions
SFA Grant, M Li, JP Bradfield, CE Kim, K … - PLos One, 2008 - pubmedcentral.nih.gov Recently an association was demonstrated between the single nucleotide
polymorphism (SNP), rs9939609, within the FTO locus and obesity as a consequence
of a genome wide association (GWA) study of type 2 diabetes in adults. We ... Cited by 20 - Related articles - All 6 versions
- ►diabetesjournals.org YC Chang, PH Liu, WJ Lee, TJ Chang, YD … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— Among the 19 SNPs, the rs9939609 A allele was strongly associated
with obesity (P = 7.0 x 10 –4 ) and BMI (P = 0.0024) in the Chinese
population. The odds ratio for obesity was 2.60 (95% CI 1.24–5.46) (P = ... Cited by 20 - Related articles - All 4 versions
J Kaput - Current Opinion in Biotechnology, 2008 - Elsevier Current nutritional and genetic epidemiological methods yield 'risk factors' on
the basis of population studies. Risk factors, however, are statistical
estimates of the percentage reduction in disease in the population if the ... Cited by 16 - Related articles - All 4 versions
