DA Vassiliadi, TM Barber, BA Hughes, MI … - Journal of Clinical Endocrinology & Metabolism, 2009 - Endocrine Soc Context: Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism,
anovulation, and susceptibility to the metabolic syndrome. Altered peripheral
cortisol metabolism has been reported in PCOS, but also in simple obesity. Related articles - All 5 versions
JK Dowman, JW Tomlinson, PN Newsome - QJM, 2009 - Oxford Univ Press In Western populations, estimates of NAFLD prevalence vary between 20 and 30%,
5,6 rising up to 90% in morbidly obese individuals. 7 The more severe, and
clinically significant form of NAFLD, non-alcoholic steatohepatitis (NASH) ...
MS Cooper, PM Stewart - Journal of Clinical Endocrinology & Metabolism, 2009 - Endocrine Soc Context: 11ß-Hydroxysteroid dehydrogenase (11ß-HSD) enzymes are now
appreciated to be im- portant regulators of hormone action at a tissue level.
11ß-HSD1 is widely expressed and increases glucocorticoid action through ... Related articles - All 3 versions
JW Tomlinson, OM Durrani, IJ Bujalska, LL … - Journal of Clinical Endocrinology & Metabolism, 2009 - Endocrine Soc Department of Endocrinology (JWT, IJB, LLG, PMS, EAW), School of Clinical and
Experimental Medicine, and Academic Unit of Ophthalmology (OMD, PJT, TTQR, SJC,
SR), School of Immunity and Infection, College of Medical and Dental ...
C Campino, CA Carvajal, J Cornejo, B San … - Springer Abstract Cortisol availability is modulated by several enzymes: 11b-HSD2, which
transforms cortisol (F) to cor- tisone (E) and 11b-HSD1 which predominantly
converts inactive E to active F. Additionally, the A-ring reductases (5a- ...