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Scholar Results 1 - 7 of 7 citing Fiorina: Targeting CD22 reprograms B-cells and reverses autoimmune diabetes. (0.05 sec) 

B cell-directed therapy for autoimmune diseases


C Hu, FS Wong, L Wen - Clin Exp Immunol, 2009 - interscience.wiley.com
B cells play an important role in the pathogenesis of both systemic and
organ-specific autoimmune diseases. Autoreactive B cells not only produce
autoantibodies, but are also specialized to efficiently present specific ...
Cited by 2 - Related articles - All 3 versions

Change you can B (cell) eive in: recent progress confirms a critical role for B cells in type 1 …


SK O'Neill, E Liu, JC Cambier - Current Opinion in Endocrinology, Diabetes and …, 2009 - journals.lww.com
Introduction The failure to find a cure for type 1 diabetes has led to the
exploration of efficacious immunotherapies already approved for other diseases.
A recent TrialNet study exploring the use of rituximab in new onset type 1 ...
Related articles - All 2 versions

Emerging roles for B lymphocytes in Type 1 diabetes


SL Cox, PA Silveira - Expert Review of Clinical Immunology, 2009 - ingentaconnect.com
Type 1 diabetes (T1D) is caused by immune infiltration of the pancreatic islets
of Langerhans (referred to as insulitis) followed by specific auto-
immune-mediated destruction of the insulin- secreting b-cells within them ...
Related articles - All 3 versions

Reduced Diabetes in btk-Deficient Nonobese Diabetic Mice and Restoration of Diabetes with …


PL Kendall, DJ Moore, C Hulbert, KL Hoek, … - The Journal of Immunology, 2009 - Am Assoc Immnol
Type 1 diabetes results from T cell-mediated destruction of insulin-producing ß
cells. Although elimination of B lymphocytes has proven successful at preventing
disease, modulation of B cell function as a means to prevent type 1 ...
Related articles - All 3 versions

Translational Mini-Review Series on B Cell-Directed Therapies: B cell-directed therapy for …


C Hu, FS Wong, L Wen - Clinical and Experimental Immunology, 2009 - pt.wkhealth.com
B cells play an important role in the pathogenesis of both systemic and
organ-specific autoimmune diseases. Autoreactive B cells not only produce
autoantibodies, but are also specialized to present specific autoantigens ...

Synthesis of biotinylated sialoside to probe CD22–ligand interactions


HHM Abdu-Allah, K Watanabe, K Hayashizaki, … - Tetrahedron Letters, 2009 - Elsevier
Synthetic ligands tagged with biotin have frequently been utilized to detect,
localize, characterize and recover the target protein. 4 Moreover, in order to
pursue CD22 as a drug target, precise and reproducible binding assays need ...
Related articles

Immunomodulatory Function of Bone Marrow-Derived Mesenchymal Stem Cells in …

- rexnealsmith.com [PDF] 
P Fiorina, M Jurewicz, A Augello, A Vergani, … - The Journal of Immunology, 2009 - Am Assoc Immnol
Human clinical trials in type 1 diabetes (T1D) patients using mesenchymal stem
cells (MSC) are presently underway without prior validation in a mouse model for
the disease. In response to this void, we characterized bone marrow-derived ...
Related articles - All 5 versions


 


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