DL Eizirik, ML Colli, F Ortis - Nature Reviews Endocrinology, 2009 - phx1.medscape.com Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease with a strong
inflammatory component. The latest studies indicate that innate immunity and
inflammatory mediators have a much broader role in T1DM than initially ... Cited by 7 - Related articles - All 8 versions
LJ Yang - Diabetes, 2008 - Am Diabetes Assoc Type 1 diabetes is conventionally thought to result from T-cell–mediated
autoimmune destruction of pancreatic β-cells (1–3). Experimental and clinical
evidence accumulated over the past two decades indicates that T-cells play ... Related articles - All 3 versions
C Gysemans, H Callewaert, F Moore, M Nelson … - Diabetologia, 2009 - Springer Abstract Aims/hypothesis IFN-γ, together with other inflammatory cytokines such
as IL-1β and TNF-α, contributes to beta cell death in type 1 diabetes. We
analysed the role of the transcription factor interferon regulatory factor ... Related articles - All 2 versions
MJ Richer, MS Horwitz - Journal of Innate Immunity, 2009 - content.karger.com To protect against viral infection, the immune response is critically dependent
on innate sensing mechanisms to provide rapid detection of pathogens and allow
for the development of an appropriate adaptive immune response. Mounting ... Related articles - All 3 versions