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Scholar Results 1 - 10 of about 33 citing van Hoek: Predicting type 2 diabetes based on polymorphisms from genome-wide association.... (0.11 sec) 

Genome-based prediction of common diseases: advances and prospects

- oxfordjournals.org
A Janssens, CM van Duijn - Human Molecular Genetics, 2008 - Oxford Univ Press
Common diseases such as type 2 diabetes and coronary heart disease result from a complex
interplay of genetic and environmental factors. Recent developments in genomics research have
boosted progress in the discovery of susceptibility genes and fueled expectations about ...
Cited by 33 - Related articles - All 3 versions

Common type 2 diabetes risk gene variants associate with gestational diabetes


J Lauenborg, N Grarup, P Damm, K Borch- … - Journal of Clinical …, 2009 - Endocrine Soc
Results: All the risk alleles in the 11 examined type 2 diabetes risk variants showed an odds
ratio (OR) greater than 1 for the GDM group compared with the control group ranging from 1.13
[95% confidence interval (CI) 0.88–1.46] to 1.44 (95% CI 1.19–1.74) except for the WFS1 ...
Cited by 3 - Related articles - All 4 versions

Population genetics and pharmacogenetics


K Ong - Yearbook of Pediatric Endocrinology 2007: Endorsed …, 2007 - books.google.com
Population Genetics and Pharmacogenetics Ken Ong Medical Research Council Epidemiology
Unit and Department of Paediatrics, University of Cambridge, Cambridge, UK With 10 million
single nucleotide polymorphisms (SNPs) to choose from it is little wonder that the vast ...
Cited by 2 - Related articles - All 5 versions

Combined analysis of 19 common validated type 2 diabetes susceptibility gene …


T Sparsø, N Grarup, C Andreasen, A Albrechtsen, J … - Diabetologia, 2009 - Springer
Abstract Aims/hypothesis The list of validated type 2 diabetes susceptibility variants has recently
been expanded from three to 19. The variants identified are common and have low penetrance
in the general population. The aim of the study is to investigate the combined effect of the ...
Cited by 2 - Related articles - All 2 versions

A common genetic variant in WFS1 determines impaired glucagon-like peptide-1- …


SA Schäfer, K Müssig, H Staiger, F Machicao, N Stefan, … - Diabetologia, 2009 - Springer
Page 1. ARTICLE A common genetic variant in WFS1 determines impaired
glucagon-like peptide-1-induced insulin secretion SA Schäfer & K. Müssig & H. Staiger
& F. Machicao & N. Stefan & B. Gallwitz & HU Häring & A. Fritsche ...
Cited by 2 - Related articles - All 2 versions

Public health genomics approach to Type 2 diabetes

- diabetesjournals.org
MJ Khoury, R Valdez, A Albright - Diabetes, 2008 - Am Diabetes Assoc
Type 2 diabetes is a leading cause of morbidity and mortality worldwide (1). In the last 15
years, the number of people in the US with diagnosed diabetes has more than doubled. Strong
risk factors for type 2 diabetes include age, sex, obesity, physical inactivity, and family ...
Cited by 2 - Related articles - All 3 versions

[PDF] Genome-based prediction of common diseases: methodological considerations for …


ACJW Janssens, CM van Duijn - Genome, 2009 - biomedcentral.com
Page 1. Genome Medicine 2009, 1:20 Review Genome-based prediction of common
diseases: methodological considerations for future research A Cecile JW Janssens*
and Cornelia M van Duijn* Address: *Department of Epidemiology ...
Cited by 4 - Related articles - View as HTML - All 9 versions

Construction of a prediction model for type 2 diabetes mellitus in the Japanese …


K Miyake, W Yang, K Hara, K Yasuda, Y … - Journal of Human …, 2009 - nature.com
Journal of Human Genetics, official journal of the Japan Society of Human
Genetics, publishes original articles and reviews on all aspects of human
genetics, including medical genetics and genomics.
Cited by 2 - Related articles - All 3 versions

[PDF] Genetic Susceptibility to Type 2 Diabetes and Implications for Therapy


JC Florez - Journal of Diabetes Science and Technology, 2009 - journalofdst.org
Since 2000, we have witnessed an explosion of known genetic determinants of type 2 diabetes
risk. These findings have seeded the expectation that our ability to make personalized,
predictive, therapeutic clinical decisions is imminent. However, the loci discovered to date ...
Cited by 1 - Related articles - View as HTML - All 2 versions

A novel similarity-measure for the analysis of genetic data in complex phenotypes


V Lagani, A Montesanto, F Di Cianni, V Moreno, … - BMC …, 2009 - biomedcentral.com
Recent technological advances in DNA sequencing and genotyping have led to the accumulation
of a remarkable quantity of data on genetic polymorphisms. However, the development of new
statistical and computational tools for effective processing of these data has not been ...
Cited by 1 - Related articles - Cached - All 5 versions


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