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Scholar Results 1 - 10 of about 28 citing Lango: Assessing the combined impact of 18 common genetic variants of modest effect sizes.... (0.09 sec) 

Genotype score in addition to common risk factors for prediction of type 2 diabetes


JB Meigs, P Shrader, LM Sullivan, JB … - The New England …, 2008 - nejm.highwire.org
From the General Medicine Division (JB Meigs, PS), the Department of Medicine (JB Meigs,
PS, JCF), and the Center for Human Genetic Research and Diabe- tes Unit, Department of Medicine
(JB McAteer, JCF), Massachusetts General Hospital, Boston; the Department of Bio- ...
Cited by 43 - Related articles - All 3 versions

Genome-based prediction of common diseases: advances and prospects

- oxfordjournals.org
A Janssens, CM van Duijn - Human Molecular Genetics, 2008 - Oxford Univ Press
Common diseases such as type 2 diabetes and coronary heart disease result from a complex
interplay of genetic and environmental factors. Recent developments in genomics research have
boosted progress in the discovery of susceptibility genes and fueled expectations about ...
Cited by 33 - Related articles - All 3 versions

Type 2 diabetes: new genes, new understanding

- cell.com
I Prokopenko, MI McCarthy, CM Lindgren - Trends in Genetics, 2008 - Elsevier
Over the past two years, there has been a spectacular change in the capacity to identify common
genetic variants that contribute to predisposition to complex multifactorial phenotypes such as
type 2 diabetes (T2D). The principal advance has been the ability to undertake surveys of ...
Cited by 15 - Related articles - All 7 versions

Nutrition and its contribution to obesity and diabetes: a life-course approach to …


ME Symonds - Proceedings of the Nutrition Society, 2008 - Cambridge Univ Press
Page 1. The Summer Meeting of the Nutrition Society was held at the University of
Nottingham on 30 June–3 July 2008 Conference on 'Multidisciplinary approaches
to nutritional problems' Symposium on 'Diabetes and health' ...
Cited by 3 - Related articles - All 2 versions

The genetics of type 2 diabetes: a realistic appraisal circa 2008

- endojournals.org [PDF] 
JC Florez - Journal of Clinical Endocrinology & Metabolism, 2008 - Endocrine Soc
Page 1. THE GENETICS OF TYPE 2 DIABETES: A REALISTIC APPRAISAL CIRCA 2008
Short title: The genetics of type 2 diabetes Jose C. Florez, MD, Ph.D. Diabetes Unit and Center
for Human Genetic Research Massachusetts General Hospital ...
Cited by 3 - Related articles

Common type 2 diabetes risk gene variants associate with gestational diabetes


J Lauenborg, N Grarup, P Damm, K Borch- … - Journal of Clinical …, 2009 - Endocrine Soc
Results: All the risk alleles in the 11 examined type 2 diabetes risk variants showed an odds
ratio (OR) greater than 1 for the GDM group compared with the control group ranging from 1.13
[95% confidence interval (CI) 0.88–1.46] to 1.44 (95% CI 1.19–1.74) except for the WFS1 ...
Cited by 3 - Related articles - All 4 versions

Genome-Wide Linkage and Admixture Mapping of Type 2 Diabetes in African …


SC Elbein, SK Das, DM Hallman, CL Hanis, SJ … - Diabetes, 2009 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—After removing outliers and problematic samples, we
conducted linkage analysis using 5,914 SNPs in 1,344 individuals from 530 families. Linkage
analysis was conducted using variance components for type 2 diabetes, age of type 2 ...
Cited by 3 - Related articles - All 5 versions

Combined analysis of 19 common validated type 2 diabetes susceptibility gene …


T Sparsø, N Grarup, C Andreasen, A Albrechtsen, J … - Diabetologia, 2009 - Springer
Abstract Aims/hypothesis The list of validated type 2 diabetes susceptibility variants has recently
been expanded from three to 19. The variants identified are common and have low penetrance
in the general population. The aim of the study is to investigate the combined effect of the ...
Cited by 2 - Related articles - All 2 versions

Risk prediction of prevalent diabetes in a Swiss population using a weighted …


X Lin, K Song, N Lim, X Yuan, T Johnson, A … - Diabetologia, 2009 - Springer
Page 1. ARTICLE Risk prediction of prevalent diabetes in a Swiss population using
a weighted genetic score—the CoLaus Study X. Lin & K. Song & N. Lim & X. Yuan &
T. Johnson & A. Abderrahmani & P. Vollenweider & H. Stirnadel & ...
Cited by 2 - Related articles - All 2 versions

The risk allele load accelerates the age-dependent decline in beta cell function


A Haupt, H Staiger, SA Schäfer, K Kirchhoff, M Guthoff, … - Diabetologia, 2009 - Springer
Page 1. ARTICLE The risk allele load accelerates the age-dependent decline in beta
cell function A. Haupt & H. Staiger & SA Schäfer & K. Kirchhoff & M. Guthoff & F.
Machicao & B. Gallwitz & N. Stefan & H.-U. Häring & A. Fritsche ...
Cited by 1 - Related articles - All 2 versions


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