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Targeting the AMPK pathway for the treatment of Type 2 diabetes


B Viollet, L Lantier, J Devin-Leclerc, S … - Frontiers in Bioscience, 2009 - pubmedcentral.nih.gov
Type 2 diabetes is one of the fastest growing public health problems worldwide
resulting from both environmental and genetic factors. It is characterized by
the abnormal glucose and lipid metabolism due in part to resistance to the ...
Cited by 5 - Related articles - All 4 versions

Molecular mechanisms involved in obesity-associated insulin resistance: Therapeutical …


S Fernandez-Veledo, I Nieto-Vazquez, R … - Archives of Physiology and Biochemistry, 2009 - ingentaconnect.com
Insulin resistance is an important contributor to the pathogenesis of type 2
diabetes (T2D) and obesity is a risk factor for its development. In the obese
state an altered secretion pattern, with increase in pro- inflammatory and ...
Related articles - All 4 versions

c-Jun N-Terminal Kinase 1/2 Activation by Tumor Necrosis Factor-{alpha} Induces Insulin …


S Fernandez-Veledo, R Vila-Bedmar, I Nieto … - Journal of Clinical Endocrinology & Metabolism, 2009 - Endocrine Soc
Results: TNF- per se increased glucose transporter-4 translocation to the plasma
membrane and glucose uptake by activating the AMP-activated protein kinase/AS160
pathway in both visceral and sc adipocytes. Nevertheless, this cytokine ...
Related articles - All 3 versions

The SLIM study: Slo-Niacin® and Atorvastatin Treatment of Lipoproteins and Inflammatory …


RH Knopp, BM Retzlaff, B Fish, A Dowdy, B … - Journal of Clinical Lipidology, 2009 - Elsevier
Mean entry lipids (in mg/dL) were as follows: TG 187, LDL-C 171, and HDL-C 39.
Mean body mass index was 32.6 kg/m 2 . Monotherapy with Slo-Niacin® decreased
median TG 15%, mean LDL-C 12%, and non-HDL-C 15% and increased HDL-C 8%. ...
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[CITATION] Selenium and diabetes: an enigma?


J PALLAUF - Free Radical Research, 2009 - Informa Healthcare
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Selenium and diabetes: an enigma?


AS Mueller, K Mueller, NM Wolf, J Pallauf - Free Radical Research, 2009 - informahealthcare.com
In recent years diabetes has become one of the most common metabolic diseases in
developed countries and it is closely related to supernutrition and obesity.
Since untreated diabetes produces oxidative stress responsible for ...
Related articles - All 2 versions

Oxidized LDL impair adipocyte response to insulin by activating serine/threonine kinases


B Scazzocchio, R Vari, M D'Archivio, C … - The Journal of Lipid Research, 2009 - ASBMB
Oxidized LDL (oxLDL) increase in patients affected by type-2 diabetes, obesity,
and metabolic syndrome. Likewise, insulin resistance, an impaired responsiveness
of target tissues to insulin, is associated with those pathological ...
Related articles - All 5 versions

Resistencia a insulina en el músculo esquelético: ejercicio y activación de receptores …

- analesranf.com [PDF] 
M Lorenzo - Monografías de la Real Academia Nacional de …, 2009 - media.analesranf.com
La resistencia a la insulina es un estado patológico que se define como la
incapacidad del organismo de responder normalmente a las acciones de la in-
sulina. Este estado está ligado a la obesidad, al estilo sedentario de ...
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