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Scholar Results 1 - 3 of 3 citing Proulx: Fatty acid synthase inhibitors modulate energy balance via mammalian target of rapamycin.... (0.07 sec) 

Mammalian target of rapamycin complex 1 (mTORC1) signaling in energy balance and …


D Cota - Physiology & Behavior, 2009 - Elsevier
Energy balance is guaranteed by a complex circuitry that in the brain, and in
the hypothalamus in particular, integrates and coordinates several types of
signals, including hormones and nutrients, so to match energy expenditure ...
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Hypothalamic lipotoxicity and the metabolic syndrome


PBM de Morentin, L Varela, J Fernø, R … - BBA-Molecular and Cell Biology of Lipids, 2009 - Elsevier
Ectopic accumulation of lipids in peripheral tissues, such as pancreatic β
cells, liver, heart and skeletal muscle, leads to lipotoxicity, a process that
contributes substantially to the pathophysiology of insulin resistance, ...
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下丘脑 mTOR 信号通路的能量平衡调节效应


陈小兰 - 白求恩军医学院学报, 2009 - journal.shouxi.net
Cota等[9]发现当大鼠进食后,下丘脑弓形核区域mTOR的活性增加
,并且其下游靶酶表达也随之增加,
说明机体能量状态可影响mTOR的活化。 ...
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