S Palomba, A Falbo, F Zullo, F Orio Jr - Endocrine Reviews, 2009 - Endocrine Soc Metformin is an insulin sensitizer widely used for the treatment of patients affected by type 2 diabetes
mellitus. Because many women with polycystic ovary syndrome (PCOS) are insulin resistant,
metformin was introduced in clinical practice to treat these patients also. Moreover, ... Cited by 13 - Related articles - All 6 versions
- ►physiology.org E Vieira, EC Nilsson, A Nerstedt, M … - American Journal of …, 2008 - Am Physiological Soc Circadian clocks coordinate physiological, behavioral, and biochemical events with predictable
daily environmental changes by a self-sustained transcriptional feedback loop. CLOCK and ARNTL
are transcriptional activators that regulate Per and Cry gene expression. PER and CRY ... Cited by 4 - Related articles - All 3 versions
- ►192.35.79.232 [PDF] JP Kirwan, TPJ Solomon, DM Wojta, MA … - American Journal of …, 2009 - Am Physiological Soc The objectives of this study were to determine whether 1) the improvement in insulin action induced
by short-term exercise training in patients with type 2 diabetes is due to an improvement in insulin
sensitivity, an improvement in insulin responsiveness, or a combination of improved ... Cited by 3 - Related articles - All 7 versions
YS Lee, DK Kim, YD Kim, KC Park, M Shong, HA … - Biochemical …, 2008 - biochemjusa.org SHP (small heterodimer partner; NR0B2) is an atypical orphan NR (nuclear receptor) that functions
as a transcriptional co- repressor by interacting with a diverse set of NRs and transcrip- tional
factors. HNF-6 (hepatocyte nuclear factor-6) is a key regu- latory factor in pancreatic ... Cited by 1 - Related articles - View as HTML - All 7 versions
- ►physiology.org D Chanda, SJ Kim, IK Lee, M Shong, … - American Journal of …, 2008 - Am Physiological Soc Sodium arsenite has been demonstrated to alter the expression of genes associated with glucose
homeostasis in tissues involved in the pathogenesis of type 2 diabetes; however, the underlying
molecular mechanism has not been fully elucidated yet. In this study, we report that the ... Cited by 1 - Related articles - All 4 versions
A Butura, K Nilsson, K Morgan, TR Morgan, SW French, … - Journal of Hepatology, 2009 - Elsevier CYP2E1 metabolizes ethanol, generates reactive oxygen species, and is suggested to be important
for development of alcoholic liver disease. The present study aims to evaluate the role of CYP2E1
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M Malaguarnera, M Di Rosa, F Nicoletti, L … - Journal of Molecular …, 2009 - Springer Abstract Non-alcoholic fatty liver disease (NAFLD) is an emerging metabolic-related disorder
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D Chanda, CH Lee, YH Kim, JR Noh, DK Kim, JH … - Hepatology, 2009 - interscience.wiley.com Plasminogen activator inhibitor type I (PAI-1) is a marker of the fibrinolytic system, and serves
as a possible predictor for hepatic metabolic syndromes. Fenofibrate, a peroxisome
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G Zhou, IK Sebhat, BB Zhang - Acta Physiologica, 2009 - interscience.wiley.com AMP-activated protein kinase (AMPK) mediated cellular metabolic responses to tissue specific
and whole body stimuli play a vital role in the control of energy homeostasis. As a cellular energy
sensing mechanism, AMPK activation stimulates glucose uptake and fat oxidation while it ... Related articles - All 3 versions
B Viollet, B Guigas, J Leclerc, S Hébrard, … - Acta physiologica ( …, 2009 - interscience.wiley.com Because the liver is central in the maintenance of glucose homeostasis and energy storage,
knowledge of the physiology as well as physiopathology of hepatic energy metabolism is a prerequisite
to our understanding of whole body metabolism. Hepatic fuel metabolism changes ... Related articles - All 3 versions
