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Scholar Results 1 - 5 of 5 citing Zhang: Fas-associated death receptor signaling evoked by human amylin in islet β-cells. (0.08 sec) 

Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis

- endojournals.org
L Haataja, T Gurlo, CJ Huang, PC Butler - Endocrine Reviews, 2008 - Endocrine Soc
Type 2 diabetes (T2DM) is characterized by insulin resistance, defective insulin
secretion, loss of β-cell mass with increased β-cell apoptosis and islet
amyloid. The islet amyloid is derived from islet amyloid polypeptide (IAPP, ...
Cited by 28 - Related articles - BL Direct - All 4 versions

Functional variants in cell death pathway genes and risk of pancreatic cancer


M Yang, T Sun, L Wang, D Yu, X Zhang, X Miao … - Clinical Cancer Research, 2008 - AACR
Results: We found a significant decrease in risk of pancreatic cancer associated
with FasL and CASP8 but not Fas polymorphisms. Compared with noncarriers, the
ORs of developing pancreatic cancer for FasL −844CT and TT carriers were ...
Cited by 11 - Related articles - BL Direct - All 3 versions

Islets in Type 2 Diabetes: In Honor of Dr. Robert C. Turner


S Bonner-Weir, TD O'Brien - Diabetes, 2008 - Am Diabetes Assoc
The UK Prospective Diabetes Study (UKPDS) orchestrated by Robert Turner showed
that, even with treatment, in type 2 diabetes a progressive β-cell dysfunction
in a large number of patients was seen with the eventual need for ...
Cited by 2 - Related articles - All 3 versions

Sphingomyelinase dependent apoptosis following treatment of pancreatic beta-cells with …


Y Zhang, F Ranta, C Tang, E Shumilina, H … - Apoptosis, 2009 - Springer
Abstract Amyloid peptides interfere with survival of pancreatic beta-cells. In
some cells apoptosis is paralleled by ceramide-dependent alterations of ion
channel activity. The purpose of the present study was to elucidate the ...
Related articles - All 2 versions

[PDF] Análisis Molecular de la Disfunción de la Célula β Pancreática en la Progresión de la …


JA Bernal - diabetes.org.ar
Page 1. Análisis molecular de la disfunción de la célula β pancreática
en la progresión de la diabetes tipo 2. Su aplicación ...
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