J Rivera, RL Proia, A Olivera - Nature reviews. Immunology, 2008 - pubmedcentral.nih.gov * The work of the authors is supported by the intramural research programs of NIAMS and
NIDDK, National Institutes of Health. We apologize to those authors whose work we could not
cite due to space constraints. ... The publisher's final edited version of this article is ... Cited by 19 - Related articles - All 4 versions
E Mariño, ST Grey - Journal of Autoimmunity, 2008 - Elsevier Type I diabetes mellitus is an autoimmune disease mediated by a selective immune-mediated
destruction of the insulin containing beta cells within the pancreatic islets of Langerhans. T cells
reactive to beta cell-derived antigens are critical for the pathogenesis of type I diabetes, ... Cited by 7 - Related articles - All 2 versions
G Zekavat, SY Rostami, A Badkerhanian, RF … - The Journal of …, 2008 - Am Assoc Immnol B lymphocytes are required for the pathogenesis of autoimmune diabetes in NOD mice. Previous
studies established that a lymphopenic transitional (TR) B cell compartment reduces the competitive
constraint on the entry of newly emerging TR B cells into the splenic follicle (FO), thereby ... Cited by 6 - Related articles - All 4 versions
FD Dufour, AG Baxter, PA Silveira - Journal of Immunotoxicology, 2008 - informahealthcare.com Type 1 diabetes is one of the most prevalent autoimmune conditions that develops during childhood
and has an increasing incidence worldwide. The disease results from the destruction of pancreatic
β cells mediated by autoreactive T-lymphocytes. In order to develop preventive therapies, ... Cited by 2 - Related articles - All 7 versions
SL Cox, PA Silveira - Expert Review of Clinical Immunology, 2009 - ingentaconnect.com Type 1 diabetes (T1D) is caused by immune infiltration of the pancreatic islets of Langerhans
(referred to as insulitis) followed by specific auto- immune-mediated destruction of the
insulin- secreting b-cells within them [1] . Predisposition to T1D depends on the ... Related articles - All 3 versions
CA Durand, K Hartvigsen, L Fogelstrand, S … - The Journal of …, 2009 - Am Assoc Immnol B-1 and marginal zone (MZ) B cells produce natural Abs, make Ab responses to microbial
pathogens, and contribute to autoimmunity. Although the isoform of the PI3K p110 catalytic subunit
is essential for development of these innate-like B cells, its role in the localization, ... Related articles - All 3 versions
M Wallberg, EA Green - Inflammation &# 38; Allergy-Drug Targets ( …, 2009 - ingentaconnect.com Abstract: Incidence of autoimmune diseases is rising rapidly in the developed world and treatment
of such diseases will be a major burden on Government health resources of the future. Whether
systemic or organ-specific, immune cell de- struction of the target tissue normally requires ... Related articles - All 2 versions
SJ Divito, AE Morelli - Phagocytosis of Dying Cells: From Molecular …, 2009 - Springer Abstract: The ability of apoptotic cells to serve as a source of alloantigen and to exert
immune-regulatory effects on the innate and adaptive immune responses make apoptotic
cell-based therapies a promising tool to down-regulate the anti-donor response that ... Related articles - All 2 versions