- ►endocrinology-journals.org M Blandino-Rosano, G Perez-Arana, JM … - Journal of Molecular Endocrinology, 2008 - Soc Endocrinology Pancreatic β-cell homeostasis is a balance between programmed cell death
(apoptosis) and regeneration. Although autoimmune diabetes mellitus type 1 (DM1)
is the most-studied cause of β-cell mass loss by pro-inflammatory cytokine- ... Cited by 4 - Related articles - All 2 versions
F Wong, L Siew, L Wen - Biochemical Society Transactions, 2008 - biochemsoctrans.org The autoimmune attack on pancreatic β-cells is orchestrated by a variety of
cells that produce cytokines and other toxic mediators. CD8 + T-cells work
together with other lymphocytes and antigen-presenting cells to mediate ... Cited by 4 - Related articles - Cached - BL Direct - All 4 versions
B Viollet, L Lantier, J Devin-Leclerc, S … - Frontiers in Bioscience, 2009 - pubmedcentral.nih.gov Type 2 diabetes is one of the fastest growing public health problems worldwide
resulting from both environmental and genetic factors. It is characterized by
the abnormal glucose and lipid metabolism due in part to resistance to the ... Cited by 5 - Related articles - All 4 versions
X Zhang, N Sun, L Wang, H Guo, Q Guan, B … - Journal of cellular and molecular medicine, 2009 - interscience.wiley.com The effect of leucine on glucose-stimulated insulin secretion (GSIS) in
pancreatic β-cells is quite controversial, and mechanism involved in the effect
has not been elucidated yet. Consequently, we aimed to investigate effect ... Cited by 2 - Related articles - All 5 versions
G Rutter, F Wong - Biochemical Society Transactions, 2008 - biochemsoctrans.org Abbreviations used: AMPK, AMP-activated protein kinase; C/EBP,
CCAAT/enhancer-binding protein; CHOP, C/EBP-homologous protein; eIF2α,
eukaryotic initiation factor 2α; ER, endoplasmic reticulum; ES, embryonic ... Cited by 1 - Related articles - Cached - BL Direct - All 4 versions
G Szabadkai, MR Duchen - Apoptosis - Springer Abstract Mitochondrial dysfunction plays a role in the pathogenesis of a wide
range of diseases that involve dis- ordered cellular fuel metabolism and
survival/death path- ways, including neurodegenerative diseases, cancer and ... Related articles - All 2 versions
A Ryan, M Murphy, C Godson, FB Hickey - Apoptosis - Springer Abstract Since the early observation that similarities between thyroiditis and
insulitis existed, the important role played by inflammation in the development
of diabetes has been appreciated. More recently, experiments have shown ... Related articles - All 2 versions
M Scharl, G Paul, KE Barrett, DF McCole - Journal of Biological Chemistry, 2009 - ASBMB Impaired epithelial barrier function plays a crucial role in the pathogenesis of
inflammatory bowel disease (IBD). Elevated levels of the proinflammatory
cytokine, interferon-gamma (IFN are believed to be prominently involved in ... Related articles - All 3 versions
KJ Claycombe, JL Goudreau, SW Yu, EK Kim - biochemjusa.org Page 1. ACTIVATION OF AUTOPHAGY THROUGH MODULATION OF AMP-ACTIVATED PROTEIN
KINASE PROTECTS PANCREATIC BETA-CELLS FROM HIGH GLUCOSE ... View as HTML
