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Scholar Results 1 - 7 of 7 citing Srinivasan: Sphingosine-1-phosphate reduces CD4+ T-cell activation in type 1 diabetes through.... (0.07 sec) 

The alliance of sphingosine-1-phosphate and its receptors in immunity


J Rivera, RL Proia, A Olivera - Nature reviews. Immunology, 2008 - pubmedcentral.nih.gov
* The work of the authors is supported by the intramural research programs of NIAMS and
NIDDK, National Institutes of Health. We apologize to those authors whose work we could not
cite due to space constraints. ... The publisher's final edited version of this article is ...
Cited by 19 - Related articles - All 4 versions

Role of sphingosine kinases and lipid phosphate phosphatases in regulating …


S Pyne, SC Lee, J Long, NJ Pyne - Cellular Signalling, 2009 - Elsevier
Sphingosine 1-phosphate (S1P) is a bioactive lipid that is produced by the sphingosine
kinase-catalysed phosphorylation of sphingosine. S1P is an important regulator of cell
function, mediating many of its effects through a family of five closely related G protein- ...
Cited by 5 - Related articles - All 2 versions

Targeting of myelin protein zero in a spontaneous autoimmune polyneuropathy


HJ Kim, CG Jung, MA Jensen, D Dukala, B … - The Journal of …, 2008 - Am Assoc Immnol
Elimination of the costimulatory molecule B7-2 prevents autoimmune diabetes in NOD mice,
but leads to the development of a spontaneous autoimmune polyneuropathy (SAP), which resembles
the human disease chronic inflammatory demyelinating polyneuropathy (CIDP). In this ...
Cited by 1 - Related articles - All 3 versions

Sphingosine-1-Phosphate: A Novel Nonhypoxic Activator of Hypoxia-Inducible …


MD Michaud, GA Robitaille, JP Gratton, DE … - … , and Vascular Biology, 2009 - Am Heart Assoc
Objective— Sphingosine-1-phosphate (S1P) is a potent bioactive phospholipid responsible for
a variety of vascular cell responses. Hypoxia-inducible factor-1 (HIF-1) is a transcriptional activator
of genes essential for adaptation to low oxygen. S1P and HIF-1 are both important ...
Related articles - All 4 versions

Clinical application of NKT cell biology in type I (autoimmune) diabetes mellitus


MT Fletcher, AG Baxter - Immunology and cell biology, 2009 - nature.com
Type 1 natural killer T (NKT) cells are a population of CD1d-restricted, regulatory T cells that
exhibit various NK cell characteristics and rapidly produce cytokines on stimulation with glycolipid
antigen. In type I diabetes (TID), NKT cells are thought to have a tolerogenic function, ...
Related articles - All 4 versions

Berberine Differentially Modulates the Activities of ERK, p38 MAPK, and JNK to …


G Cui, X Qin, Y Zhang, Z Gong, B Ge, YQ Zang - Journal of Biological Chemistry, 2009 - ASBMB
Berberine, an alkaloid derivative from Berberis vulgaris L., has been used extensively in traditional
Chinese medicine to treat diarrhea and diabetes, but the underlying mechanisms for treating
diabetes are not fully understood. Recent studies suggested that berberine has many ...
Cited by 1 - Related articles - All 3 versions

Lyase to live by: Sphingosine phosphate lyase as a therapeutic target


A Kumar, JD Saba - Expert Opin. Ther. Targets, 2009 - informahealthcare.com
Background: Sphingosine 1-phosphate (S1P) is a bioactive lipid that regulates cell
proliferation, survival and migration and plays an essential role in angiogenesis and lymphocyte
trafficking. S1P levels in the circulation and tissues are tightly regulated for proper cell ...
Related articles - All 6 versions


 


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