JRB Perry, TM Frayling - Current Opinion in Clinical Nutrition & Metabolic Care, 2008 - journals.lww.com Recent findings: Recent genome-wide association studies have provided an
important resource for furthering our understanding of type 2 diabetes disease
mechanisms. Genes previously unsuspected of playing a role in diabetes are ... Cited by 17 - Related articles - All 2 versions
H Staiger, F Machicao, K Kantartzis, SA … - PLoS ONE, 2008 - pubmedcentral.nih.gov Genome-wide association (GWA) studies identified a series of novel type 2
diabetes risk loci. Most of them were subsequently demonstrated to affect
insulin secretion of pancreatic β-cells. Very recently, a meta-analysis of ... Cited by 10 - Related articles - All 6 versions
- ►diabetesjournals.org MI McCarthy, AT Hattersley - Diabetes, 2008 - Am Diabetes Assoc Genetic factors for many decades have been known to play a critical role in the
etiology of diabetes, but it has been only recently that the specific genes have
been identified. The identification of the underlying molecular genetics ... Cited by 9 - Related articles - All 4 versions
MJ Groenewoud, JM Dekker, A Fritsche, E … - Diabetologia, 2008 - Springer Abstract Aims/hypothesis Genome-wide association studies have recently
identified novel type 2 diabetes susceptibility gene regions. We assessed the
effects of six of these regions on insulin secretion as determined by a ... Cited by 6 - Related articles - All 3 versions
SM Ruchat, CE Elks, RJF Loos, MC Vohl, SJ … - Acta Diabetologica, 2009 - Springer Page 1. ORIGINAL ARTICLE Association between insulin secretion, insulin sensitivity
and type 2 diabetes susceptibility variants identified in genome-wide ... Cited by 5 - Related articles - All 2 versions
H Staiger, F Machicao, SA Schäfer, K Kirchhoff … - PLoS ONE, 2008 - pubmedcentral.nih.gov We genotyped 1,578 non-diabetic subjects, metabolically characterized by oral
glucose tolerance test, for five tagging single nucleotide polymorphisms (SNPs)
covering 100% of common genetic variation (minor allele frequency >0.05) ... Cited by 4 - Related articles - All 6 versions
B Friedrich, P Weyrich, A Stančáková, J … - PLoS ONE, 2008 - pubmedcentral.nih.gov Copyright Friedrich et al. This is an open-access article distributed under the
terms of the Creative Commons Attribution License, which permits unrestricted
use, distribution, and reproduction in any medium, provided the original ... Cited by 4 - Related articles - All 6 versions
NJ Timpson, CM Lindgren, MN Weedon, J … - Diabetes, 2009 - Am Diabetes Assoc RESULTS—In the “obese-type 2 diabetes” scan, FTO variants had the
strongest type 2 diabetes effect (rs8050136: relative risk [RR] 1.49 [95% CI
1.34–1.66], P = 1.3 × 10 −13 ), with only weak evidence for TCF7L2 ( ... Cited by 4 - Related articles - All 3 versions
AL Gloyn, MI McCarthy - Diabetic Medicine, 2008 - interscience.wiley.com The identification and functional characterisation of genetic variants that
either cause or predispose to diabetes is a major focus of biomedical research.
The molecular basis is now known for the majority of monogenic forms of ... Cited by 3 - Related articles - All 3 versions
O Pivovarova, VJ Nikiforova, AF Pfeiffer, N … - Diabetes Metab Res Rev, 2009 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 2 - Related articles - All 2 versions
