- ►endojournals.org X Xu, S Jhun… - Endocrinology, 2008 - Endocrine Soc Metabolic syndrome accelerates the atherosclerotic process, and the earliest
event of which is endothelial dysfunction. Ghrelin, a newly discovered gastric
peptide, improves endothelial function and inhibits proatherogenic changes. ... Cited by 17 - Related articles - All 5 versions
S Palomba, A Falbo, F Zullo, F Orio Jr - Endocrine Reviews, 2009 - Endocrine Soc Metformin is an insulin sensitizer widely used for the treatment of patients
affected by type 2 diabetes mellitus. Because many women with polycystic ovary
syndrome (PCOS) are insulin resistant, metformin was introduced in clinical ... Cited by 13 - Related articles - All 6 versions
S Gundewar, JW Calvert, S Jha, I Toedt- … - Circulation Research, 2009 - Am Heart Assoc Clinical studies have reported that the widely used antihyperglycemic drug
metformin significantly reduces cardiac risk factors and improves clinical
outcomes in patients with heart failure. The mechanisms by which metformin ... Cited by 8 - Related articles - All 6 versions
- ►sinica.edu.tw [PDF] Z Chen, I Peng… - Circulation Research, 2009 - Am Heart Assoc Endothelial nitric oxide synthase (eNOS) plays a central role in maintaining
cardiovascular homeostasis by controlling NO bioavailability. The activity of
eNOS in vascular endothelial cells (ECs) largely depends on ... Cited by 4 - Related articles - All 6 versions
AS Kim, EJ Miller, LH Young - Acta Physiologica, 2009 - ingentaconnect.com Over the past decade, AMP-activated protein kinase (AMPK) has emerged as an
important intracellular signalling pathway in the heart. Activated AMPK
stimulates the production of ATP by regulating key steps in both glucose ... Cited by 3 - Related articles
- ►cardiovascres.org G Kewalramani, P Puthanveetil, F Wang, MS … - Cardiovascular Research, 2009 - cardiovascres.oxfordjournals.org Methods and results: Cardiomyocytes were incubated with DEX, MET, or TNF- for
varying durations (0–12 h). TNF- -induced cell damage was evaluated by
measuring caspase-3 activity and Hoechst staining. Protein and gene ... Cited by 3 - Related articles - All 5 versions
- ►nih.gov Y Wang, E Gao, L Tao, WB Lau, Y Yuan, BJ … - Circulation, 2009 - Am Heart Assoc Methods and Results— Male adult mice with cardiomyocyte-specific
overexpression of a mutant AMPK 2 subunit (AMPK-DN) or wild-type (WT)
littermates were subjected to in vivo myocardial ischemia/reperfusion ... Cited by 1 - Related articles - All 9 versions
CDL Folmes, CS Wagg, M Shen, AS … - American Journal of Physiology- Heart and Circulatory …, 2009 - Am Physiological Soc Activation of 5'-AMP-activated protein kinase (AMPK) may benefit the heart
during ischemia-reperfusion by increasing energy production. While AMPK
stimulates glycolysis, mitochondrial oxidative metabolism is the major ... Cited by 1 - Related articles - All 3 versions
AKF Wong, J Howie, JR Petrie, CC Lang, 2009 - ukpmc.ac.uk AMPK (AMP-activated protein kinase) is a heterotrimetric enzyme that is
expressed in many tissues, including the heart and vasculature, and plays a
central role in the regulation of energy homoeostasis. It is activated in ... Cited by 2 - Related articles - All 8 versions
