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Scholar Results 1 - 8 of 8 citing Tikellis: ACE2 deficiency modifies renoprotection afforded by ACE inhibition in experimental.... (0.08 sec) 

Angiotensin-converting enzyme 2: implications for blood pressure and kidney disease

- problemsinanes.com
JR Ingelfinger - Current Opinion in Nephrology and Hypertension, 2009 - journals.lww.com
Recent findings: A substantial body of research indicates that ACE2 is
cardioprotective and renoprotective. ACE2 participates in a pathway that is
counterregulatory to the effects of angiotensin II (Ang II). The mechanisms ...
Cited by 4 - Related articles - All 5 versions

Agents in development for the treatment of diabetic nephropathy


SY Goh, M Jasik, ME Cooper - Expert Opin. Emerging Drugs, 2008 - informahealthcare.com
Background: Nephropathy is a major cause of morbidity and mortality in diabetic
patients. Current treatments include optimization of glycemic and blood pressure
control, but more innovative strategies are needed for the prevention and ...
Related articles - All 6 versions

Pharmacologic modulation of ACE2 expression


MJ Soler, C Barrios, R Oliva, D Batlle - Current Hypertension Reports, 2008 - Springer
Introduction Angiotensin-converting enzyme 2 (ACE2) is a carboxy- peptidase that
cleaves the peptides angiotensin (Ang) I and II, apelin, and neurotensin [1 ].
The ACE2 gene is mapped in the human X chromosome (Xp22) and con- tains 18 ...
Related articles - All 2 versions

Albumin caused the increasing production of angiotensin II due to the dysregulation of ACE …


BC Liu, J Gao, Q Li, LM Xu - Clinica Chimica Acta, 2009 - Elsevier
Treatment of HK-2 cells to BSA led to a significant increasing expression of ACE
mRNA in dose and time dependent manner. The overexpression of ACE protein
induced by BSA was consistent with its mRNA expression. Meanwhile, the mRNA ...
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Not just angiotensinases: new roles for the angiotensin-converting enzymes


DW Lambert, NE Clarke, AJ Turner - Cellular and Molecular Life Sciences - Springer
Abstract The renin-angiotensin system (RAS) is a criti- cal regulator of blood
pressure and fluid homeostasis. Angiotensin II, the primary bioactive peptide of
the RAS, is generated from angiotensin I by angiotensin-converting enzyme ...
Related articles - All 2 versions

The role of ACE2 in pulmonary diseases--relevance for the nephrologist


GY Oudit, Y Imai, K Kuba, JW Scholey, JM … - Nephrology Dialysis Transplantation, 2009 - ERA-EDTA
The renin–angiotensin system (RAS) is a central regulator of cardiovascular
and renal functions and plays a key role in the pathophysiology of various
cardiovascular and renal diseases. The RAS consists of a series of ...
Cited by 1 - Related articles - All 6 versions

Therapeutic Strategies in the Treatment of Diabetic Nephropathy-a Translational Medicine …


IM Shah, SP Mackay, GA McKay - Current medicinal chemistry, 2009 - ingentaconnect.com
1 Strathclyde Institute of Pharmacy and Biomedical Sciences, University of
Strathclyde, Glasgow, Scotland, G4 0NR, UK 2 University Medical Unit, Glasgow
Royal Infirmary, Castle Street, Glasgow, Scotland, G4 0SF, UK Abstract: ...
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血管紧张素转换酶 2 与糖尿病肾病


章容, 李素梅 - 国际内分泌代谢杂志, 2009 - cqvip.com
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