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Zinc transporter-8 gene (SLC30A8) is associated with type 2 diabetes in Chinese

- endojournals.org
J Xiang, XY Li, M Xu, J Hong, Y Huang, JR Tan, … - Journal of Clinical …, 2008 - Endocrine Soc
Results: A significant association for SNP rs13266634 was observed between patients with type
2 diabetes and NGT controls (P = 0.016). The association was also observed between combined
type 2 diabetes/IGR and NGT subjects (P = 0.002). The adjusted odds ratios for ...
Cited by 11 - Related articles - All 3 versions

Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, …


YH Lee, ES Kang, SH Kim, SJ Han, CH Kim, HJ … - Journal of human …, 2008 - Springer
Abstract According to recent genome-wide association studies, a number of single nucleotide
polymorphisms (SNPs) are reported to be associated with type 2 diabetes mellitus (T2DM). The
aim of the present study was to investigate the association among the polymorphisms of ...
Cited by 9 - Related articles - All 6 versions

Zinc signalling and subcellular distribution: emerging targets in type 2 diabetes


E Mocchegiani, R Giacconi, M Malavolta - Trends in molecular medicine, 2008 - Elsevier
A finely tuned subcellular distribution of zinc (Zn), through the coordinated action of Zn transporters
(ZnTs) and metallothioneins (MTs), is crucial for optimal cell function. Dysfunctions of these proteins
might act as key causative or promoting factors in several chronic pathologies. Evidence ...
Cited by 5 - Related articles - All 5 versions

Genetic prediction of renal transplant outcome

- problemsinanes.com
AS Goldfarb-Rumyantzev, N Naiman - Current Opinion in Nephrology …, 2008 - journals.lww.com
Recent findings: Recent studies are based on the candidate gene analysis; specifically, cytokine
genes and innate immune response molecules present popular targets for studies of acute rejection
and long-term outcome. Pharmacogenomic studies are mostly focused on the genes of ...
Cited by 2 - Related articles - All 6 versions

Zinc-dependent effects of small molecules on the insulin-sensitive transcription …


AR Cameron, S Anil, E Sutherland, J Harthill, G Rena - rsc.org
Metal-binding compounds have recently been reported to have anti-hyperglycaemic properties
in vivo. In the current study, we have investigated the ability of these compounds and related
structures to induce insulin-like signal transduction to downstream effectors such as the ...
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Zn 2-transporter-8: A dual role in diabetes


DA Chistiakov, NV Voronova - interscience.wiley.com
Diabetes mellitus arises from defects in insulin secretion or action, or both. In pancreatic
islets, insulin production is linked with zinc transport mediated by zinc transporter ZnT-8, a product
of the SLC30A8 gene. Therefore, altered activity of ZnT-8 is expected to be associated ...
Related articles

Zn (2+)-transporter-8: a dual role in diabetes.


DA Chistiakov, NV Voronova - BioFactors (Oxford, England) - ncbi.nlm.nih.gov
Diabetes mellitus arises from defects in insulin secretion or action, or both. In pancreatic
islets, insulin production is linked with zinc transport mediated by zinc transporter ZnT-8, a product
of the SLC30A8 gene. Therefore, altered activity of ZnT-8 is expected to be associated ...
Related articles

Association of Common Type 2 Diabetes Risk Gene Variants and …


ES Kang, MS Kim, CH Kim, CM Nam, SJ Han, KY Hur, … - Transplantation, 2009 - pt.wkhealth.com
New-onset posttransplantation diabetes mellitus (PTDM) is a common complication after renal
transplantation and is associated with increased cardiovascular morbidity, patient mortality, and
graft loss (1–3). The reported incidence of PTDM varies, because of a lack of standard ...

Association of Common Type 2 Diabetes Risk Gene Variants and …


ES Kang, MS Kim, CH Kim, CM Nam, SJ Han, KY Hur … - Transplantation, 2009 - journals.lww.com
New-onset posttransplantation diabetes mellitus (PTDM) is a common complication after renal
transplantation and is associated with increased cardiovascular morbidity, patient mortality, and
graft loss (1–3). The reported incidence of PTDM varies, because of a lack of standard ...
Related articles - All 3 versions

New-onset diabetes after transplantation: a review of recent literature


A Balla, M Chobanian - Current Opinion in Organ Transplantation, 2009 - journals.lww.com
Introduction New-onset diabetes after transplantation (NODAT) remains a serious complication
with a high reported incidence. It is a major independent risk factor for cardiovascular disease
[1]. Individuals may experience glucose intolerance and remain asymptomatic for years ...
Related articles - All 4 versions


 


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