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Scholar Results 1 - 6 of 6 citing Niehof: HNF4α and the Ca-Channel TRPC1 Are Novel Disease Candidate Genes in Diabetic Nephropathy. (0.11 sec) 

Physiology and pathophysiology of canonical transient receptor potential channels


J Abramowitz, L Birnbaumer - The FASEB Journal, 2009 - FASEB
The existence of a mammalian family of TRPC ion channels, direct homologues of
TRP, the visual transduction channel of flies, was discovered during 1995–1996
as a consequence of research into the mechanism by which the stimulation of ...
Cited by 9 - Related articles - All 4 versions

Defining human diabetic nephropathy on the molecular level: Integration of transcriptomic …


S Martini, F Eichinger, V Nair, M Kretzler - Reviews in Endocrine & Metabolic Disorders, 2008 - Springer
Abstract Diabetic nephropathy (DN) is the most common cause for end stage renal
disease (ESRD). Next to environmental factors, genetic predispositions determine
the susceptibility for DN and its rate of progression to ESRD. With the ...
Cited by 2 - Related articles - All 2 versions

Evaluation of Genetic Association and Expression Reduction of TRPC1 in the Development …

- nih.gov
D Zhang, BI Freedman, M Flekac, E Santos, … - American journal of nephrology, 2008 - content.karger.com
Background/Aims: The TRPC1 gene on chromosome 3q22-24 resides within the linkage
region for diabetic nephropathy (DN) in type 1 (T1D) and type 2 diabetes
mellitus (T2D). A recent study has demonstrated that TRPC1 expression is ...
Cited by 2 - Related articles - All 5 versions

Molecular characterization of lung dysplasia induced by c-raf-1


A Rohrbeck, VS Müller, J Borlak - PloS one, 2009 - pubmedcentral.nih.gov
We employed laser microdissection to harvest c-Raf1- induced dysplastic as
opposed to transgenic but otherwise morphologically unaltered epithelium and
compared findings to non-transgenic lung. We then employed microarrays to ...
Cited by 1 - Related articles - All 4 versions

HNF4alpha and HNF1alpha Dysfunction as a Molecular Rational for Cyclosporine Induced …


J Borlak, M Niehof - PLoS ONE, 2009 - pubmedcentral.nih.gov
Posttransplantation diabetes mellitus (PTDM) is a frequent complication in
immunosuppressive therapy. To better understand the molecular events associated
with PTDM we investigated the effect of cyclosporine on expression and ...
Related articles - All 4 versions

Expression of HNF4alpha in the human and rat choroid plexus–Implications for drug …


M Niehof, J Borlak - BMC Molecular Biology, 2009 - pubmedcentral.nih.gov
The choroid plexus consists of highly differentiated epithelium and functions as
a barrier at the interface of the blood-cerebrospinal-fluid (CSF). This tissue
may therefore determine the bioavailability and transport of drugs to the ...
Related articles - All 5 versions


 


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