A Willcox, SJ Richardson, AJ Bone, AK … - Clin Exp Immunol, 2009 - interscience.wiley.com The immunopathology of type 1 diabetes (T1D) has proved difficult to study in
man because of the limited availability of appropriate samples, but we now
report a detailed study charting the evolution of insulitis in human T1D. ... Cited by 6 - Related articles - All 3 versions
E Mariño, ST Grey - Journal of Autoimmunity, 2008 - Elsevier Type I diabetes mellitus is an autoimmune disease mediated by a selective
immune-mediated destruction of the insulin containing beta cells within the
pancreatic islets of Langerhans. T cells reactive to beta cell-derived ... Cited by 6 - Related articles - All 2 versions
J Chen, X Liu - Cellular Immunology, 2009 - Elsevier Interferon γ (IFNγ) plays a central role in the immune response against
infection and tumur immune surveillance. Its functions include not only
activation of the host immune system to control microbial infections but ... Cited by 4 - Related articles - All 3 versions
DM Tarlinton, F Batista, KGC Smith - Transplantation, 2008 - journals.lww.com Transplantation. Wolters Kluwer Health Logo. All Issues. ... Cited by 2 - Related articles - All 2 versions
FD Dufour, AG Baxter, PA Silveira - Journal of Immunotoxicology, 2008 - informahealthcare.com Type 1 diabetes is one of the most prevalent autoimmune conditions that develops
during childhood and has an increasing incidence worldwide. The disease results
from the destruction of pancreatic β cells mediated by autoreactive T- ... Cited by 2 - Related articles - All 7 versions
SL Cox, PA Silveira - Expert Review of Clinical Immunology, 2009 - ingentaconnect.com Type 1 diabetes (T1D) is caused by immune infiltration of the pancreatic islets
of Langerhans (referred to as insulitis) followed by specific auto-
immune-mediated destruction of the insulin- secreting b-cells within them ... Related articles - All 3 versions
A Ryan, M Murphy, C Godson, FB Hickey - Apoptosis - Springer Abstract Since the early observation that similarities between thyroiditis and
insulitis existed, the important role played by inflammation in the development
of diabetes has been appreciated. More recently, experiments have shown ... Related articles - All 2 versions
CB Sanjeevi - International Journal of Diabetes in Developing …, 2009 - ijddc.com A recent report published in Lancet [2] indicates that T1D incidence has doubled
and is likely to double from now to year 2020 in those aged below five years and
increase 70% in those below 15 years. There is an annual increase in ... Related articles - Cached - All 3 versions
C Ionescu-Tîrgoviºte - Acta Endocrinologica (Buc), 2009 - 82.76.72.38 Abstract Based on epidemiological, clinic, biochemical and hormonal data (both
personal and international), our personal view is that natural history of
autoimmune type 1 diabetes could include the following stages: 1) The ... Related articles - View as HTML - All 2 versions
M Wallberg, EA Green - Inflammation &# 38; Allergy-Drug Targets (Formerly …, 2009 - ingentaconnect.com Abstract: Incidence of autoimmune diseases is rising rapidly in the developed
world and treatment of such diseases will be a major burden on Government health
resources of the future. Whether systemic or organ-specific, immune cell ... Related articles - All 2 versions
