- ►endojournals.org M Boni-Schnetzler, J Thorne, G Parnaud, L … - Journal of Clinical …, 2008 - Endocrine Soc Results: Gene array analysis of RNA from β-cells of individuals with T2DM revealed increased
expression of IL-1β mRNA. Real-time PCR confirmed increased IL-1β expression in six of 10
T2DM samples, with minimal or no expression in nine control samples. In cultured human ... Cited by 8 - Related articles - All 4 versions
JP Palmer - Diabetes Metab Res Rev, 2009 - interscience.wiley.com Type 1 diabetes is diagnosed when the patient's endogenous insulin secretion decreases to
a level which results in hyperglycemia. After diagnosis, insulin secretion continues to
decline. As a reference for clinical trials trying to preserve endogenous beta-cell function ... Cited by 2 - Related articles - All 2 versions
- ►endojournals.org [PDF] M Boni-Schnetzler, J Thorne, G Parnaud, L … - Journal of Clinical …, 2008 - Endocrine Soc 1 Clinic of Endocrinology and Diabetes, University Hospital of Zurich, 8091 Zurich, Switzerland
2 Section of Islet Transplantation and Cell Biology, Joslin Diabetes Center, Harvard Medical
School, Boston, Massachusetts 02215, USA 3 Department of Genetic Medicine and ... Cited by 1 - Related articles
C Pfleger, G Meierhoff, H Kolb, NC Schloot - Journal of Autoimmunity, 2009 - Elsevier 50 adults and 49 children (mean age 27.3 and 10.9 years respectively) with recent onset type
1 diabetes who participated in a placebo-controlled trial of immune intervention with DiaPep277
were analyzed. Secretion of interferon (IFN)-γ, interleukin (IL)-5, IL-13 and IL-10 by single ... Related articles - All 2 versions
H Kolb, T Mandrup-Poulsen - Diabetologia - Springer Abstract The recent major increase in the global incidence of type 2 diabetes suggests that most
cases of this disease are caused by changes in environment and lifestyle. All major risk factors
for type 2 diabetes (overnutrition, low dietary fibre, sedentary lifestyle, sleep deprivation ...
HK Bid, R Konwar, CG Agrawal, M Banerjee - Indian Journal of Medical …, 2008 - Medknow The nature of association of IL-4 and IL-1RN polymorphisms with, and their combined effect
on, Indian T2DM patients is not known. As a first step to evaluate whether these cytokines' polymorphisms
have functional influence on the susceptibility to T2DM, we conducted a study of the ... Cited by 1 - Related articles - Cached - All 9 versions
[CITATION] Challenges in developing endpoints for type 1 diabetes intervention studies …
S Cernea, I Raz, KC Herold, B … - Diabetes/ …, 2009 - John Wiley & Sons, Ltd. Chichester, …
H Aly, P Gottlieb - Current Opinion in Endocrinology, Diabetes and …, 2009 - journals.lww.com Introduction Although 'type 1 diabetes' had been first described by Himsworth in 1936 [1], its
treatment so far has been mainly insulin replacement with little success in tackling the underlying
disease pathology. Part of the problem is the lack of clear knowledge of disease ... Related articles - All 2 versions
HB Mortensen, PG Swift, RW Holl, P Hougaard, L … - Pediatric …, 2008 - ncbi.nlm.nih.gov HB Mortensen, PGF Swift, RW Holl, P Hougaard, L Hansen, H Bjoerndalen, CE de Beaufort,
M Knip. Multinational study in children and adolescents with newly diagnosed type 1
diabetes: association of age, ketoacidosis, HLA status, and autoantibodies on residual ... Related articles
V Volarevic, A Al-Qahtani, N Arsenijevic, S Pajovic, ML … - Autoimmunity - informahealthcare.com The increase of pro-inflammatory cytokines and oxidative stress leads to β-cell damage and
promotes β-cells apoptosis, in types I and II of diabetes mellitus. Therefore, blocking of pro-inflammatory
cytokines should be an effective way for the treatment of diabetes mellitus. When IL-1 ... Related articles
