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Scholar Results 1 - 10 of about 27 citing Zhang: Serum FGF21 levels are increased in obesity and are independently associated with.... (0.07 sec) 

Causes and metabolic consequences of fatty liver


N Stefan, K Kantartzis, HU Haring - Endocrine Reviews, 2008 - Endocrine Soc
Type 2 diabetes and cardiovascular disease represent a serious threat to the health of the population
worldwide. Although overall adiposity and particularly visceral adiposity are established risk
factors for these diseases, in the recent years fatty liver emerged as an additional and ...
Cited by 15 - Related articles - All 4 versions

Plasma concentrations of fibroblast growth factors 19 and 21 in patients with …

- endojournals.org
I Dostalova, P Kavalkova, D Haluzikova, Z … - Journal of Clinical …, 2008 - Endocrine Soc
Context: Fibroblast growth factor 19 (FGF19) and FGF21 are novel metabolic regulators that
improve insulin sensitivity and decrease adiposity in mice. However, little is known about the
nutritional regulation of these factors in humans. ... Objective: The objective of this study ...
Cited by 11 - Related articles - All 3 versions

Circadian expression of FGF21 is induced by PPARα activation in the mouse liver


K Oishi, D Uchida, N Ishida - FEBS letters, 2008 - Elsevier
Peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor that regulates the
expression of genes associated with lipid metabolism. Recent studies have suggested that the
expression of PPARα-dependent fibroblast growth factor 21 (FGF21) plays important ...
Cited by 7 - Related articles - All 5 versions

Different roles of N-and C-termini in the functional activity of FGF21


R Micanovic, DW Raches, JD Dunbar, DA Driver, … - J Cell …, 2009 - interscience.wiley.com
Fibroblast growth factor 21 is a member of endocrine FGFs subfamily, along with FGF19 and
FGF23. It is emerging as a novel regulator with beneficial effects on a variety of metabolic
parameters, including glucose and lipid control. FGF21 activity depends on membrane ...
Cited by 5 - Related articles - All 2 versions

Serum Fibroblast Growth Factor 21 Is Associated with Adverse Lipid Profiles and { …


H Li, Y Bao, A Xu, X Pan, J Lu, H Wu, H Lu, K … - Journal of Clinical …, 2009 - Endocrine Soc
Design: Serum FGF21 levels were determined by ELISA in 134 normal glucose tolerance
(NGT), 101 isolated-impaired fasting glucose, and 118 isolated-impaired glucose tolerance
(I-IGT) Chinese subjects, and their association with parameters of adiposity, glucose, and ...
Cited by 5 - Related articles - All 3 versions

Fibroblast Growth Factor 21 Controls Glycemia via Regulation of Hepatic Glucose …


ED Berglund, CY Li, HA Bina, SE Lynes, MD Michael, … - Endocrinology, 2009 - Endocrine Soc
Fibroblast growth factor 21 (FGF21) is a novel metabolic regulator shown to improve glycemic
control. However, the molecular and functional mechanisms underlying FGF21-mediated improvements
in glycemic control are not completely understood. We examined FGF21 effects on insulin ...
Cited by 3 - Related articles - All 3 versions

Temas de actualidad en prevención cardiovascular y rehabilitación cardiaca


M León-Latre, P Mazón-Ramos, E Marcos, E García- … - Rev Esp Cardiol, 2009 - revespcardiol.org
En este artículo se revisan los principales avances publicados en la prevención de las enfermedades
cardiovasculares en el último año, así como los nuevos documentos de consenso. Como en
años precedentes, buena parte del esfuerzo investigador está relacionado con las ...
Cited by 2 - Related articles - Cached - All 5 versions

Circulating FGF21 is induced by PPAR agonists but not ketosis in Man


C Christodoulides, P Dyson, D Sprecher, K … - Journal of Clinical …, 2009 - Endocrine Soc
1 Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford,
UK. 2 NIHR Oxford Biomedical Research Centre, ORH Trust, Churchill Hospital, Oxford, UK 3
Cardiovascular and Urogenital Centre for Excellence in Drug Discovery, ...
Cited by 1 - Related articles - All 2 versions

Fibroblast growth factor 21: an overview from a clinical perspective


M Rydén - Cellular and Molecular Life Sciences, 2009 - Springer
Abstract Fibroblast growth factor 21 (FGF21) has been proposed as a novel putative therapeutic
agent in type 2 diabetes. A large amount of data, predominantly obtained from murine models
but also from non-human primates, suggest that FGF21 ameliorates obesity-associated ...
Cited by 1 - Related articles - All 2 versions

Serum levels of the adipokine FGF21 depend on renal function


S Stein, A Bachmann, U Lössner, J Kratzsch, M … - Diabetes Care, 2009 - Am Diabetes Assoc
OBJECTIVE—To investigate renal elimination of the adipokine fibroblast growth factor 21
(FGF21) by determining circulating FGF21 levels in patients on chronic hemodialysis (CD) as
compared with control subjects with a glomerular filtration rate (GFR) >50 ml/min.
Cited by 1 - Related articles - All 3 versions


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