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Scholar Results 1 - 10 of 12 citing Valenti: Increased expression and activity of the transcription factor FOXO1 in nonalcoholic.... (0.07 sec) 

FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice


A Kamagate, S Qu, G Perdomo, D Su, DH Kim … - The Journal of Clinical Investigation, 2008 - pubmedcentral.nih.gov
Excessive production of triglyceride-rich VLDL is attributable to
hypertriglyceridemia. VLDL production is facilitated by microsomal triglyceride
transfer protein (MTP) in a rate-limiting step that is regulated by ...
Cited by 16 - Related articles - BL Direct - All 7 versions

Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)


G Musso, R Gambino, M Cassader - Progress in Lipid Research, 2009 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver
disease in Western countries and is considered the hepatic manifestation of
metabolic syndrome. The hallmark of NAFLD is hepatic neutral lipid ...
Cited by 7 - Related articles - All 2 versions

New Insights on the Xenobiotic-Sensing Nuclear Receptors in Liver Diseases-CAR and …


S Kakizaki, Y Yamazaki, D Takizawa, M … - Current Drug Metabolism, 2008 - ingentaconnect.com
Abstract: The xenobiotic receptors CAR and PXR constitute two important members
of the NR1I nuclear receptor family. They function as sensors of toxic
byproducts derived from the endogenous metabolism and of exogenous ...
Cited by 7 - Related articles - All 2 versions

Insulin resistance and steatosis in humans


J Capeau - Diabetes and Metabolism, 2008 - Elsevier
Insulin resistance is commonly found in a large number of adults—in
particular, those with android obesity, the metabolic syndrome or type 2
diabetes. Strong adverse relationships between adipose tissue, liver and ...
Cited by 4 - Related articles - All 3 versions

Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose …


R Menghini, S Menini, R Amoruso, L Fiorentino … - Gastroenterology, 2009 - Elsevier
Obesity-driven, low-grade inflammation affects systemic metabolic function and
can lead to insulin resistance, hepatic steatosis, and atherosclerosis.
Decreased expression of tissue inhibitor of metalloproteinase 3 (Timp3) is ...
Cited by 4 - Related articles - All 3 versions

FoxO1 integrates insulin signaling to VLDL production


A Kamagate, HH Dong - Cell cycle (Georgetown, Tex.), 2008 - pubmedcentral.nih.gov
Very low-density lipoproteins (VLDL) are triglyceride-rich particles. VLDL is
synthesized in hepatocytes and secreted from the liver in a pathway that is
tightly regulated by insulin. Hepatic VLDL production is stimulated in ...
Cited by 3 - Related articles - All 4 versions

The immunopathogenesis of alcoholic and nonalcoholic steatohepatitis: two triggers for one …


L Valenti, A Ludovica Fracanzani, S Fargion - Seminars in Immunopathology, 2009 - Springer
Abstract Alcoholic liver disease and nonalcoholic liver disease represent a
leading cause of liver disease and share similar pathogenic mechanisms among
which activation of the immune system plays a key role. The main events ...
Cited by 1 - Related articles - All 2 versions

Molecular mechanisms involved in NAFLD progression


M Malaguarnera, M Di Rosa, F Nicoletti, L … - Journal of Molecular Medicine, 2009 - Springer
Abstract Non-alcoholic fatty liver disease (NAFLD) is an emerging
metabolic-related disorder characterized by fatty infiltration of the liver in
the absence of alcohol consump- tion. NAFLD ranges from simple steatosis to ...
Cited by 2 - Related articles - All 2 versions

[CITATION] 45 Non-alcoholic Fatty Liver Disease: A Pathophysiological Perspective


M Fuchs, AJ Sanyal
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[CITATION] Risk of severe liver disease in nonalcoholic fatty liver disease: Role of insulin resistance


AL Fracanzani, L Valenti, S Fargion - Hepatology - interscience.wiley.com
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