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Scholar Results 1 - 10 of about 45 citing Forbes: Oxidative stress as a major culprit in kidney disease in diabetes. (0.07 sec) 

Interactions Between Advanced Glycation End-Products (AGE) and their Receptors …


KC Sourris, JM Forbes - Current Drug Targets, 2009 - ingentaconnect.com
Abstract: Diabetes, is a metabolic disorder characterised by chronic hyperglycaemia,
hypertension, dyslipidaemia, micro- albuminuria and inflammation. Moreover, there are a number
of complications associated with this condition including retinopathy, neuropathy and ...
Cited by 3 - Related articles - All 2 versions

Targeting the protein kinase C family in the diabetic kidney: lessons from analysis …


M Meier, J Menne, H Haller - Diabetologia, 2009 - Springer
Abstract The protein kinase C (PKC) superfamily com- prises proteins that are activated in response
to various pathogenic stimuli in the diabetic state. Hyperglycaemia is the predominant stimulus
that induces the activation of distinct PKC isoforms within a cell, each mediating specific ...
Cited by 3 - Related articles - All 2 versions

Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin …


W Bakker, EC Eringa, P Sipkema, VWM van … - Cell and Tissue …, 2009 - Springer
Abstract Endothelial dysfunction comprises a number of functional alterations in the vascular
endothelium that are associated with diabetes and cardiovascular disease, including changes
in vasoregulation, enhanced generation of reactive oxygen intermediates, inflammatory ...
Cited by 4 - Related articles - All 4 versions

Renal Protective Effect of Metabolic Therapy in Patients with Coronary Artery …


R Thuillier, JP Tillement, T Hauet - Current pharmaceutical design, 2009 - ingentaconnect.com
Abstract: Coronary artery disease (CAD) is due to subintimal deposition of atheromatous plaques
in large and medium- sized coronary arteries. Different risk factors have been identified such
as hypertension, hypercholesterolemia, diabetes and smoking. Both hypertension and ...
Cited by 2 - Related articles - All 3 versions

Low Aerobic Capacity and High-Fat Diet Contribute to Oxidative Stress and IRS-1 …


EM Morris, AT Whaley-Connell, JP Thyfault, SL … - Am J Nephrol, 2009 - content.karger.com
Background/Aims: Insulin receptor (IR- and IR- ) is reduced in the kidney of insulin-resistant
rodents. It is unknown if there are also reductions in insulin receptor substrate (IRS)-1 or if these
effects are due to metabolic injury. Thereby, we hypothesized intrinsically high aerobic ...
Cited by 2 - Related articles - All 4 versions

Impact of Early Onset Obesity and Hypertension on the Unfolded Protein Response …


D Sharkey, HP Fainberg, V Wilson, E Harvey, DS … - Hypertension, 2009 - Am Heart Assoc
Childhood obesity has reached epidemic proportions. Obesity is an independent risk factor for
the development of end-stage renal disease. Endoplasmic reticulum stress and subsequent
activation of the unfolded protein response (UPR) are implicated in the development of ...
Cited by 1 - Related articles - All 5 versions

Zinc supplementation partially prevents renal pathological changes in diabetic rats


Y Tang, Q Yang, J Lu, X Zhang, D Suen, Y Tan, L … - The Journal of Nutritional …, 2009 - Elsevier
We have demonstrated that Zn supplementation mediated up-regulation of cardiac metallothionein
(MT) as a potent antioxidant prevented the development of diabetic cardiomyopathy. The present
study was undertaken to test whether induction of renal MT synthesis by Zn ...
Cited by 1 - Related articles

Hyperglycemia and Glycation in Diabetic Complications


A Negre-Salvayre, R Salvayre, N Augé, R … - Antioxidants & Redox … - liebertonline.com
To cite this article: Anne Negre-Salvayre, Robert Salvayre, Nathalie Augé, Reinald
Pamplona, Manuel Portero-Otín, Nader Abraham, Melvin Hayden, Rafael Nagler, James
Sowers, Oren Tirosh, Zhiguo Wang. Antioxidants & Redox Signaling. -Not available-, ...
Related articles - All 3 versions

Advanced oxidation protein products: a causative link between oxidative stress and …


Y Liu - Kidney International, 2009 - nature.com
Advanced oxidation protein products (AOPPs), a protein biomarker of increased oxidative
stress, are elevated in uremic patients. Zhou et al. demonstrate that chronic administration of
AOPPs induces podocyte apoptosis and proteinuria in normal rats via a cascade of ...

Altered metabolism of copper, zinc, and magnesium is associated with increased …


A Viktorínová, E Tošerová, M Križko, Z Ďuračková - Metabolism, 2009 - Elsevier
Diabetes mellitus (DM) is associated with the alterations in the metabolism of copper (Cu), zinc
(Zn), and magnesium (Mg). The aim of the present study was to investigate plasma levels of these
elements in patients with DM and in healthy subjects. Association between glycated ...
Related articles - All 13 versions


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