A Kalliokoski, JT Backman, PJ Neuvonen, M … - Pharmacogenetics and …, 2008 - journals.lww.com Cited Here...: The AUC 0-∞ and C max of repaglinide were 32% (P=0.007) and 24% lower
(P=0.056) in the individuals with the SLCO1B1*1B/*1B genotype than in those with the
SLCO1B1*1A/*1A genotype. The mean blood glucose concentration from 0 to 7 h after ... Cited by 6 - Related articles - All 3 versions
MA Pacanowski, CW Hopley, CL … - Expert Opin. Drug Metab …, 2008 - informahealthcare.com Background: Numerous effective oral pharmacologic therapies are available to treat type 2
diabetes. However, a substantial number of patients do not achieve the expected glucose-lowering
response, or may be predisposed to adverse effects, from these agents. The application ... Cited by 2 - Related articles - BL Direct - All 6 versions
… , M Neuvonen, PJ Neuvonen, M Niemi - British Journal of …, 2008 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 2 - Related articles - All 4 versions
O Zolk, TF Solbach, J Konig, MF Fromm - Drug Metabolism and Disposition, 2009 - ASPET The organic cation transporter 2 (OCT2, SLC22A2) plays an important role for renal drug
elimination. Recent clinical studies indicate an impact of the frequent nonsynonymous
c.808G>T (p.270Ala>Ser) polymorphism on renal clearance of metformin and the extent ... Cited by 1 - Related articles - All 3 versions
P Sharma, VE Holmes, R Elsby, C Lambert, D Surry - Xenobiotica, 2009 - informahealthcare.com The kinetics of OATP1B1-mediated uptake of [ 3 H]-oestradiol 17β-glucuronide and inhibition
of uptake by rifamycin SV were used to determine K m , V max , and IC 50 values over a range
of passage numbers to investigate accuracy and precision. The mean K m and V max ...
I Bachmakov, H Glaeser, B Endress, F … - Diabetes, Obesity …, 2009 - interscience.wiley.com Aim:The uptake of drugs from the blood into the renal tubular cells is a key determinant for renal
secretion and may influence their systemic plasma concentrations and extrarenal effects.
Metformin, used for treatment of type 2 diabetes, is taken up into renal tubular cells by the ... Related articles - All 3 versions
A Kalliokoski, M Niemi - British Journal of Pharmacology, 2009 - interscience.wiley.com Membrane transporters are now recognized as important determinants of the transmembrane
passage of drugs. Organic anion transporting polypeptides (OATP) form a family of influx transporters
expressed in various tissues important for pharmacokinetics. Of the 11 human OATP ... Cited by 1 - Related articles - All 3 versions
J Kindla, MF Fromm, J König - Expert Opin. Drug Metab. Toxicol., 2009 - informahealthcare.com Background: Transport proteins, for example the drug export pump P-glycoprotein, are important
for the absorption, distribution and excretion of drugs. Inhibition and induction of P-glycoprotein
efflux function is a well-established mechanism of drug–drug interactions. Alteration of ... Related articles - All 7 versions
K Mandery, K Bujok, I Schmidt, T Wex, G Treiber, P … - Journal of Pharmacology …, 2009 - ASPET Page 1. JPET #154518 1 Influence of cyclooxygenase inhibitors on the function of the
prostaglandin transporter OATP2A1 expressed in human gastroduodenal mucosa # Kathrin
Mandery, Krystyna Bujok, Ingrid Schmidt, Thomas Wex, Gerhard Treiber, Peter ... Related articles - All 2 versions
- ►biologists.org A Mulenga, R Khumthong, KC Chalaire, O … - Journal of …, 2008 - jeb.biologists.org The organic anion transporting polypeptides (Oatps in rodents and other organism; OATPs in
human) are Na + -independent transporters that shuttle a wide range of endogenous and xenobotic
amphipathic compounds across plasma membranes. We previously discovered an ... Related articles - All 4 versions
