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Scholar Results 1 - 10 of about 16 citing Busik: Hyperglycemia-induced reactive oxygen species toxicity to endothelial cells is dependent.... (0.10 sec) 

Methylglyoxal-Induced Increase in Peroxynitrite and Inflammation Related to Diabetes

- usask.ca [PDF] 
H Wang, 2009 - library2.usask.ca
Page 1. METHYLGLYOXAL-INDUCED INCREASE IN PEROXYNITRITE AND INFLAMMATION RELATED
TO DIABETES A Thesis Submitted to the College of Graduate Studies and Research ...
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Activation of PKC-δ and SHP-1 by hyperglycemia causes vascular cell apoptosis and …


P Geraldes, J Hiraoka-Yamamoto, M Matsumoto, … - Nature Medicine, 2009 - nature.com
Cellular apoptosis induced by hyperglycemia occurs in many vascular cells and is
crucial for the initiation of diabetic pathologies. In the retina, pericyte
apoptosis and the formation of acellular capillaries, the most specific ...

Methylglyoxal-induced mitochondrial dysfunction in vascular smooth muscle cells


H Wang, J Liu, L Wu - Biochemical Pharmacology, 2009 - Elsevier
The effects of methylglyoxal (MG) on mitochondria with specific foci on
peroxynitrite (ONOO − ) production, manganese superoxide dismutase (MnSOD)
activity, and mitochondrial functions in vascular smooth muscle A-10 cells ...
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Islet Endothelial Activation and Oxidative Stress Gene Expression Is Reduced by IL-1Ra …


G Lacraz, MH Giroix, N Kassis, J Coulaud, A …, 2009 - pubmedcentral.nih.gov
Gene expression was analyzed by quantitative RT-PCR on islets isolated from
10-week-old diabetic GK and control Wistar rats. Furthermore, GK rats were
treated sc twice daily with IL-1Ra (Kineret, Amgen, 100 mg/kg/day) or ...
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MITOCHONDRIAL DYSFUNCTION IN DIABETES: FROM MOLECULAR MECHANISMS TO …


WI Sivitz, MA Yorek - Antioxidants & Redox Signaling - liebertonline.com
Page 1. 1 COMPREHENSIVE INVITED REVIEW MITOCHONDRIAL DYSFUNCTION IN DIABETES: FROM
MOLECULAR MECHANISMS TO FUNCTIONAL SIGNIFICANCE AND THERAPEUTIC OPPORTUNITIES ...
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High glucose and oxidative/nitrosative stress conditions induce apoptosis in retinal …

- uc.pt [PDF] 
EC Leal, CA Aveleira, AF Castilho, AM Serra, … - Experimental Eye Research, 2009 - Elsevier
Diabetic retinopathy (DR) is a leading cause of vision loss among working-age
adults. Retinal endothelial cell apoptosis is an early event in DR, and
oxidative stress is known to play an important role in this pathology. ...
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Oxidative stress and the development of diabetic retinopathy: Contributory role of matrix …


RA Kowluru, M Kanwar - Free Radical Biology and Medicine, 2009 - Elsevier
Matrix metalloproteinases (MMPs) degrade extracellular matrix and regulate many
functions including cell signaling. Oxidative stress is implicated in the
development of diabetic retinopathy, and MMP-2, the most ubiquitous member ...
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Multiple mechanisms of soy isoflavones against oxidative stress-induced endothelium injury


SZ Xu, W Zhong, M Ghavideldarestani, R … - Free Radical Biology and Medicine, 2009 - Elsevier
Diabetic vascular complications are related to a combination of oxidative stress
and hyperglycemia. Here we investigate the effect and mechanism of soy
isoflavones on oxidative stress-induced endothelial cell injury. Oxidative ...
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Effects of Angiotensin Receptor Blocker on Oxidative Stress and Cardio-Renal Function in …

- wdc-jp.com [PDF] 
W Arozal, K Watanabe, PT Veeraveedu, M Ma … - Biological & Pharmaceutical Bulletin, 2009 - J-STAGE
It is becoming increasingly evident that cumulative oxida- tive stress has a
very close relationship with the progression of many human diseases such as
diabetes mellitus (DM), car- diovascular diseases, and cancer.1) It has ...
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Differential Regulation of High Glucose-Induced Glyceraldehyde-3-Phosphate Dehydrogenase …


ECK Yego, JA Vincent, V Sarthy, JV Busik, S … - Investigative Ophthalmology & Visual Science, 2009 - ARVO
RESULTS. High glucose induced IL-1β, weak IL-6, and no TNF production by rMC-1
and HMCs. IL-1β (1–10 ng/mL) significantly increased GAPDH nuclear
accumulation in Müller cells in a concentration-dependent manner within 24 ...
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