- ►nih.gov D Sandoval - Physiology & behavior, 2008 - Elsevier Current models hold that peripheral and CNS GLP-1 signaling operate as distinct
systems whereby CNS GLP-1 regulates food intake and circulating GLP-1 regulates
glucose homeostasis. There is accumulating evidence that the arcuate ... Cited by 6 - Related articles - All 4 versions
- ►glucagon.com [PDF] JE Ayala, DP Bracy, FD James, BM Julien, … - Endocrinology, 2009 - Endocrine Soc Glucagon-like peptide-1 (GLP-1) diminishes postmeal glucose excursions by
enhancing insulin secretion via activation of the β-cell GLP-1 receptor
(Glp1r). GLP-1 may also control glucose levels through mechanisms that are ... Cited by 6 - Related articles - All 4 versions
- ►diabetesjournals.org C Cabou, G Campistron, N Marsollier, C … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— A continuous 3-h brain infusion of Ex4 decreased femoral arterial
blood flow and whole-body glucose utilization in the awake free-moving mouse
clamped in a hyperinsulinemic-hyperglycemic condition, only demonstrating ... Cited by 6 - Related articles - All 5 versions
S Mudaliar, RR Henry - European Journal of Internal Medicine, 2009 - Elsevier Impaired insulin secretion plays a major role in the pathogenesis of type 2
diabetes mellitus, and progressive loss of β-cell function is a
pathophysiologic hallmark of type 2 diabetes. Recent science has elaborated ... Cited by 3 - Related articles - All 38 versions
EB Ruttimann, M Arnold, JJ Hillebrand, N … - Endocrinology, 2009 - Endocrine Soc Peripheral administration of glucagon-like peptide (GLP)-1 reduces food intake
in animals and humans, but the sites and mechanism of this effect and its
physiological significance are not yet clear. To investigate these issues, ... Cited by 2 - Related articles - All 2 versions
KA Simpson, NM Martin, S R. Bloom - Arquivos Brasileiros de Endocrinologia & Metabologia, 2009 - SciELO Brasil Current estimates suggest that over 1 billion people are overweight and over 300
million people are obese. Weight gain is due to an imbalance between energy
expenditure and dietary intake. This review discusses the hypothalamic ... Cited by 1 - Related articles - Cached - All 7 versions
MR Hayes, L Bradley, HJ Grill - Endocrinology, 2009 - Endocrine Soc Page 1. 1 Endogenous hindbrain GLP-1 receptor activation contributes to the control
of food intake by mediating gastric satiation signaling ... Cited by 1 - Related articles - All 2 versions
MR Hayes, L Bradley, HJ Grill - Endocrinology, 2009 - Endocrine Soc Exogenous activation of central nervous system glucagon-like peptide-1 (GLP-1)
receptors (GLP-1Rs) reduces food intake. Experiments addressed whether
endogenous central GLP-1R activity is involved in the control of normal ... Related articles
CME Tracker - medscape.com Glucagon-like peptide (GLP)-1 was discovered incidentally following the cloning
of proglucagon, and has been one of the most studied regulatory peptides in the
field of metabolism over the last 2 decades. [1] The most compelling ... Related articles
