- ►oxfordjournals.org MI McCarthy, JN Hirschhorn - Human Molecular Genetics, 2008 - Oxford Univ Press Genome-wide association studies have successfully identified numerous loci at which common
variants influence disease risk or quantitative traits. Despite these successes, the variants identified
by these studies have generally explained only a small fraction of the heritable ... Cited by 30 - Related articles - All 3 versions
Y Wu, H Li, RJF Loos, Z Yu, X Ye, L Chen, A Pan, FB … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— We confirmed the associations between type 2 diabetes and variants near CDKAL1
(odds ratio 1.49 [95% CI 1.27–1.75]; P = 8.91 × 10 −7 ) and CDKN2A/B (1.31 [1.12–1.54]; P =
1.0 × 10 −3 ). We observed significant association of SNPs in IGF2BP2 (1.17 [1.03–1.32]; ... Cited by 28 - Related articles - All 5 versions
MI McCarthy - Nature genetics, 2008 - nature.com Jump to main content; Jump to navigation; nature.com homepage; Publications AZ index;
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Nature Genetics homepage Search This journal Advanced search. ... Cited by 15 - Related articles - All 4 versions
- ►cell.com I Prokopenko, MI McCarthy, CM Lindgren - Trends in Genetics, 2008 - Elsevier Over the past two years, there has been a spectacular change in the capacity to identify common
genetic variants that contribute to predisposition to complex multifactorial phenotypes such as
type 2 diabetes (T2D). The principal advance has been the ability to undertake surveys of ... Cited by 15 - Related articles - All 7 versions
JCN Chan, V Malik, W Jia, T Kadowaki, CS Yajnik, KH … - Jama, 2009 - Am Med Assoc You are seeing this message because your Web browser does not support basic Web
standards. Find out more about why this message is appearing and what you can do to make
your experience on this site better. ... Add to CiteULike Add to Connotea Add to ... Cited by 14 - Related articles - All 4 versions
YH Lee, ES Kang, SH Kim, SJ Han, CH Kim, HJ … - Journal of human …, 2008 - Springer Abstract According to recent genome-wide association studies, a number of single nucleotide
polymorphisms (SNPs) are reported to be associated with type 2 diabetes mellitus (T2DM). The
aim of the present study was to investigate the association among the polymorphisms of ... Cited by 9 - Related articles - All 6 versions
R Rong, RL Hanson, D Ortiz, C Wiedrich, S Kobes, WC … - Diabetes, 2009 - Am Diabetes Assoc RESULTS—FTO provided the strongest evidence for replication, where SNPs were associated
with type 2 diabetes (odds ratio = 1.20 per copy of the risk allele, P = 0.03) and BMI (P =
0.002). None of the other previously reported SNPs were associated with type 2 diabetes; ... Cited by 7 - Related articles - All 3 versions
- ►endojournals.org AIF Blakemore, P Froguel - Journal of Clinical Endocrinology & …, 2008 - Endocrine Soc Evidence Synthesis: The current genetic evidence in obesity underlines the importance of neuroendocrine
mechanisms of appetite regulation. Monogenic forms of disease explain 6% of children with
extreme obesity, having hyperphagia associated with defects in the leptin-melanocortin ... Cited by 6 - Related articles - All 3 versions
S Cauchi, F Stutzmann, C Cavalcanti-Proença, E … - Journal of Molecular …, 2009 - Springer Page 1. RAPID COMMUNICATION Combined effects of MC4R and FTO common
genetic variants on obesity in European general populations Stéphane Cauchi & Fanny
Stutzmann & Christine Cavalcanti-Proença & Emmanuelle ... Cited by 4 - Related articles - All 2 versions
