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CT60 and+ 49 polymorphisms of CTLA 4 are associated with ANCA-positive small vessel …


L Kamesh, JM Heward, JM Williams, SCL … - Rheumatology, 2009 - Br Soc Rheumatology
Add to CiteULike Add to Connotea Add to Del.icio.us What's this? ... 1 Renal
Unit, University Hospitals Birmingham NHS Foundation Trust, 2 Division of
Immunity and Infection, The Medical School, University of Birmingham, ...
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CT60 and þ49 polymorphisms of CTLA 4 are associated with ANCA-positive small vessel …


L Kamesh, JM Heward, JM Williams, SCL … - Rheumatology - Br Soc Rheumatology
Objective. To investigate whether single nucleotide polymorphisms (SNPs) within
cytotoxic T-lymphocyte antigen-4 (CTLA-4) are associated with ANCA-associated
small vessel vasculitis (SVV). Methods. The CTLA-4 CT60 (exon 4), þ49 ...
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Remodeling rodent models to mimic human type 1 diabetes


M von Herrath, GT Nepom, B Coalition - European Journal of Immunology, 2009 - interscience.wiley.com
Type 1 diabetes (T1D) occurs when the immune system attacks the
insulin-producing beta cells located in the islets of Langerhans within the
pancreas. Animal models have played a prominent role in developing an ...
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Genetic-induced Variations in the GAD65 T-cell Repertoire Governs Efficacy of Anti-CD3/ …


D Bresson, M Fradkin, Y Manenkova, D … - Molecular Therapy, 2009 - nature.com
To enhance efficacy of forthcoming type 1 diabetes (T1D) clinical trials,
combination therapies (CTs) are envisaged. In this study, we showed that
efficacy of a CT, using anti-CD3 antibody and glutamic acid decarboxylase ...
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