H Shimano - FEBS J, 2009 - interscience.wiley.com Sterol regulatory element-binding proteins (SREBPs) have been established as physiological
regulators of lipid synthesis. The molecular mechanisms by which cellular sterol balance and
nutritional states regulate SREBP activities are the current research focus of this field. ... Cited by 6 - Related articles - All 4 versions
- ►umin.ac.jp [PDF] M Ishikawa, Y Iwasaki, S Yatoh, T Kato, S … - The Journal of Lipid …, 2008 - ASBMB To determine the role of cholesterol synthesis in pancreatic β-cells, a transgenic model of in vivo
activation of sterol-regulatory element binding protein 2 (SREBP-2) specifically in β-cells
(TgRIP-SREBP-2) was developed and analyzed. Expression of nuclear human SREBP-2 ... Cited by 2 - Related articles - All 7 versions
GL Wang, YC Fu, WC Xu, YQ Feng, SR Fang, XH … - … and Biophysical Research …, 2009 - Elsevier Recent studies in mice have shown that resveratrol can protect the liver from fat accumulation
induced by high fat diet. However, the exact mechanism is largely unknown. To explore the possible
mechanism, we investigated the anti-lipogenic effect of resveratrol in vitro model. Oil Red ... Cited by 1 - Related articles - All 2 versions
M Ishikawa, Y Iwasaki, S Yatoh, T Kato, S Kumadaki, N … - The Journal of Lipid … - ASBMB Page 1. 1 Overexpression of nuclear SREBP-2 in pancreatic β-cells results in cholesterol
accumulation leading to insulin secretion defects and diabetes :A new model for β-cell lipotoxicity
Mayumi Ishikawa1, Yuko Iwasaki1, Shigeru Yatoh1, Toyonori Kato1, Shin Kumadaki1, ... Related articles - All 2 versions
Y Iwasaki, H Iwasaki, S Yatoh, M Ishikawa, T Kato, … - … and Biophysical Research …, 2009 - Elsevier Transgenic mice expressing nuclear sterol regulatory element-binding protein-1a under the control
of the insulin promoter were generated to determine the role of SREBP-1a in pancreatic
β-cells. Only low expressors could be established, which exhibited mild hyperglycemia, ... Related articles - All 2 versions
KH Hellemans, JC Hannaert, B Denys, KR Steffensen, … - 2009 - pubmedcentral.nih.gov Chronically elevated levels of fatty acids-FA can cause beta cell death in vitro. Beta cells vary
in their individual susceptibility to FA-toxicity. Rat beta cells were previously shown to better resist
FA-toxicity in conditions that increased triglyceride formation or mitochondrial and ... Related articles - All 4 versions
B Ashibe, K Motojima - FEBS Journal, 2009 - interscience.wiley.com Fatty aldehyde dehydrogenase (FALDH; also known as ALDH3A2 or ALDH10) oxidizes
medium- or long-chain aliphatic aldehydes. FALDH deficiency in humans is known to be the
cause of Sjögren–Larsson syndrome, in which individuals display neurological symptoms ...
T Cvjeticanin, I Stojanovic, G Timotijevic, S Stosic- … - BMC …, 2009 - biomedcentral.com This Provisional PDF corresponds to the article as it appeared upon acceptance. Fully formatted
PDF and full text (HTML) versions will be made available soon. ... T cells cooperate with palmitic
acid in induction of beta cell apoptosis ... Tamara Cvjeticanin (cvjetica@gmail.com) Ivana ... Related articles - View as HTML - All 5 versions
S Shao, Z Fang, X Yu, M Zhang - Biochemical and Biophysical Research …, 2009 - Elsevier GSIS, the most important function of pancreatic beta cell, is essential for maintaining the glucose
homeostasis. Transcription factors are known to control different biological processes such as
differentiation, proliferation and apoptosis. In pancreas, some transcription factors are ... Related articles - All 2 versions
AJ Fernández-Alvarez - 2009 - digital.csic.es Page 1. CARACTERIZACIÓN ESTRUCTURAL Y FUNCIONAL DE LOS PROMOTORES
HUMANOS SREBP1 Y SU REGULADOR INSIG2 Memoria presentada por Ana Julia
Fernández-Alvarez para optar al grado de Doctor en Bioquímica Valencia, 2009 ... Related articles - View as HTML - All 2 versions