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Scholar Results 1 - 3 of 3 citing Fawcett: Evaluating the role of LPIN1 variation in insulin resistance, body weight, and human.... (0.09 sec) 

Thematic Review Series: Glycerolipids. Multiple roles for lipins/phosphatidate …


K Reue, DN Brindley - The Journal of Lipid Research, 2008 - ASBMB
Phosphatidate phosphatase-1 (PAP1) enzymes have a key role in glycerolipid synthesis through
the conversion of phosphatidate to diacylglycerol, the immediate precursor of triacylglycerol,
phosphatidylcholine, and phosphatidylethanolamine. PAP1 activity in mammals is ...
Cited by 10 - Related articles - All 7 versions

Lipin proteins and metabolic homeostasis


K Reue, JR Dwyer - The Journal of Lipid Research, 2009 - ASBMB
The lipin protein family consists of three members, lipin-1, lipin-2, and lipin-3. The founding member
of the family, lipin-1, was identified via positional cloning as the mutated gene product in the
fatty liver dystrophy (fld) mouse (1). The name of the mutation refers to the occurrence of ...
Cited by 3 - Related articles - All 5 versions

Biochemistry, physiology, and genetics of GPAT, AGPAT, and lipin enzymes in …


K Takeuchi, K Reue - American Journal of Physiology- …, 2009 - Am Physiological Soc
Triacylglycerol (TAG) synthesis and storage in tissues such as adipose tissue and liver have
important roles in metabolic homeostasis. The molecular identification of genes encoding enzymes
that catalyze steps in TAG biosynthesis from glycerol 3-phosphate has revealed an ...
Cited by 2 - Related articles - All 4 versions


 


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