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Scholar Results 1 - 10 of 12 citing Wang: Skeletal muscle–specific deletion of lipoprotein lipase enhances insulin signaling.... (0.13 sec) 

Type 2 diabetes, mitochondrial biology and the heart


MN Sack - Journal of Molecular and Cellular Cardiology, 2009 - Elsevier
Diabetes is recognized as an independent risk factor for cardiovascular
morbidity and mortality. This is due, in large part, to premature
atherosclerosis, enhanced thrombogenicity and activation of systemic ...
Cited by 3 - Related articles - All 21 versions

Lipoprotein lipase: from gene to obesity


H Wang, RH Eckel - American Journal of Physiology- Endocrinology And …, 2009 - Am Physiological Soc
Lipoprotein lipase (LPL) is a multifunctional enzyme produced by many tissues,
including adipose tissue, cardiac and skeletal muscle, islets, and macrophages.
LPL is the rate-limiting enzyme for the hydrolysis of the triglyceride (TG) ...
Cited by 3 - Related articles - All 4 versions

Fat Partitioning and Insulin Sensitivity


MJ Watt, EW Kraegen - Diabetes, 2009 - Am Diabetes Assoc
The evidence is now compelling that an excess supply of fatty acids, beyond that
required for energy needs, is a cause of muscle insulin resistance.
Intramyocellular triglyceride accumulation is a marker of excess fatty acid ...
Cited by 1 - Related articles - All 3 versions

[PDF] David H. Wasserman, Julio E. Ayala, and Owen P. McGuinness


PIN DIABETES - mc.vanderbilt.edu
There are few methodologies that have done more to advance our understanding of
insulin action in humans and animals than the hyperinsulinemic- euglycemic clamp
(henceforth referred to as the insulin clamp or clamp). The clamp was first ...
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Constitutive expression of suppressor of cytokine signalling-3 in skeletal muscle leads to …


P Lebrun, E Cognard, R Bellon-Paul, P Gontard … - Diabetologia, 2009 - Springer
Abstract Aims/hypothesis Due to their ability to regulate various signalling
pathways (cytokines, hormones, growth factors), the suppressor of cytokine
signalling (SOCS) proteins are thought to be promising therapeutic targets ...
Related articles - All 2 versions

PPARs and the orchestration of metabolic fuel selection


MC Sugden, MG Zariwala, MJ Holness - Pharmacological Research, 2009 - Elsevier
This contribution describes recent advances in our knowledge of the regulatory
interactions between the two major oxidative fuels glucose and lipid. It also
addresses how the metabolic abnormalities associated with insulin ...
Related articles - All 2 versions

Journal List> J Korean Endocr Soc> v. 24 (2); Jun 2009


HW Shin, HW Jang, KS Kim, JI Lee, JY Park, … - J Korean Endocr Soc, 2009 - synapse.koreamed.org
Surgical excision is the only effective treatment of medullary thyroid carcinoma
(MTC) and there is no certain treatment for recurrence or distant metastasis.
Materials that influence MTC cell proliferation were recently reported. ...
Related articles - Cached - All 2 versions

Skeletal muscle insulin resistance: the interplay of local lipid excess and mitochondrial …


L Chow, A From, E Seaquist - Metabolism, 2009 - Elsevier
The prevalence of type 2 diabetes mellitus (DM2) is increasing precipitously as
a consequence of the aging population and obesity epidemic. Type 2 diabetes
mellitus is characterized by both pancreatic β-cell dysfunction and ...
Related articles - All 2 versions

Inflammation, Insulin Resistance, and Type 2 Diabetes: Back to the Future?


WT Cefalu - Diabetes, 2009 - Am Diabetes Assoc
In this issue of Diabetes, two articles highlight the emergence of
inflammation's contribution to insulin resistance and to chronic diseases in
humans. The common feature in each article is the inflammation–obesity– ...
Related articles - All 3 versions

Insulin Stimulates the Expression of Carbohydrate Response Element Binding Protein ( …


AS Sirek, L Liu, M Naples, K Adeli, DS Ng, T … - Endocrinology, 2009 - Endocrine Soc
The carbohydrate response element binding protein (ChREBP) has been recognized
as a key controller of hepatic lipogenesis. Whereas the function of ChREBP has
been extensively investigated, mechanisms underlying its transcription ...
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