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Scholar Results 1 - 10 of about 15 citing Xu: Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure,.... (0.07 sec) 

Circulating FGF21 is induced by PPAR agonists but not ketosis in Man


C Christodoulides, P Dyson, D Sprecher, K … - Journal of Clinical Endocrinology & Metabolism, 2009 - Endocrine Soc
1 Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital,
Oxford, UK. 2 NIHR Oxford Biomedical Research Centre, ORH Trust, Churchill
Hospital, Oxford, UK 3 Cardiovascular and Urogenital Centre for Excellence ...
Cited by 1 - Related articles - All 2 versions

Fibroblast growth factor 21: an overview from a clinical perspective


M Rydén - Cellular and Molecular Life Sciences, 2009 - Springer
Abstract Fibroblast growth factor 21 (FGF21) has been proposed as a novel
putative therapeutic agent in type 2 diabetes. A large amount of data,
predominantly obtained from murine models but also from non-human primates, ...
Cited by 1 - Related articles - All 2 versions

Fibroblast Growth Factor-19, a Novel Factor That Inhibits Hepatic Fatty Acid Synthesis


S Bhatnagar, HA Damron, FB Hillgartner - Journal of Biological Chemistry, 2009 - ASBMB
Previous studies have shown that administration of fibroblast growth factor-19
(FGF-19) reverses diabetes, hepatic steatosis, hyperlipidemia, and adipose
accretion in animal models of obesity. To investigate the mechanism for ...
Cited by 1 - Related articles - All 3 versions

Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse …


J Xu, S Stanislaus, N Chinookoswong, YY Lau, … - American Journal of Physiology- Endocrinology And …, 2009 - Am Physiological Soc
Recombinant fibroblast growth factor (FGF)21 has antihyperglycemic,
antihyperlipidemic, and antiobesity effects in diabetic rodent and monkey
models. Previous studies were confined to measuring steady-state effects of ...
Related articles - All 3 versions

Circulating Fibroblast Growth Factor 21 Is Induced by Peroxisome Proliferator-Activated …


C Christodoulides, P Dyson, D Sprecher, K … - Journal of Clinical Endocrinology & Metabolism, 2009 - Endocrine Soc
Context: Murine fibroblast growth factor (FGF) 21 is a nutritionally regulated
hormone secreted by the liver principally in response to peroxisome
proliferator-activated receptor- (PPAR ) activation, which plays a critical ...
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[PDF] David H. Wasserman, Julio E. Ayala, and Owen P. McGuinness


PIN DIABETES - mc.vanderbilt.edu
There are few methodologies that have done more to advance our understanding of
insulin action in humans and animals than the hyperinsulinemic- euglycemic clamp
(henceforth referred to as the insulin clamp or clamp). The clamp was first ...
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Glucose induces FGF21 mRNA expression through ChREBP activation in rat hepatocytes


K Iizuka, J Takeda, Y Horikawa - FEBS letters, 2009 - Elsevier
Fibroblast growth factor 21 (FGF21) has beneficial effects of improving the
plasma glucose and lipid profiles in diabetic rodents. Here, we investigated
carbohydrate response element binding protein (ChREBP) involvement in the ...
Related articles - All 9 versions

The Role of Mitochondria in the Pathophysiology of Skeletal Muscle Insulin Resistance


I Pagel-Langenickel, J Bao, L Pang, MN Sack - Endocrine Reviews, 2009 - Endocrine Soc
Multiple organs contribute to the development of peripheral insulin resistance,
with the major contributors being skeletal muscle, liver, and adipose tissue.
Because insulin resistance usually precedes the development of type 2 ...

Hypocaloric high-protein diet improves fatty liver and hypertriglyceridemia in sucrose-fed …


T Uebanso, Y Taketani, M Fukaya, K Sato, Y … - American Journal of Physiology- Endocrinology And …, 2009 - Am Physiological Soc
The mechanism by which replacement of some dietary carbohydrates with protein
during weight loss favors lipid metabolism remains obscure. In this study, we
investigated the effect of an energy-restricted, ...
Related articles - All 4 versions

[PDF] NOVEL INSIGHTS INTO METABOLIC REGULATION BY GLUCAGON RECEPTOR …


E Berglund, 2009 - etd.library.vanderbilt.edu
Page 1. NOVEL INSIGHTS INTO METABOLIC REGULATION BY GLUCAGON RECEPTOR ACTIVATION –
INDUCTION OF HEPATIC ENERGY-DEPLETION AND AMPK SIGNALING By Eric Berglund ...
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