Web Images Videos Maps News Shopping Gmail more »
Sign in
Scholar Home  
  Advanced Scholar Search
Scholar Preferences
Scholar Results 1 - 9 of 9 citing Lee: Overexpression of SIRT1 Protects Pancreatic {beta}-Cells Against Cytokine Toxicity by.... (0.09 sec) 

JANEX-1, a JAK3 inhibitor, protects pancreatic islets from cytokine toxicity through …


N Lv, EK Kim, MY Song, HN Choi, WS Moon, … - Experimental cell research, 2009 - Elsevier
JANEX-1/WHI-P131, a selective Janus kinase 3 (JAK3) inhibitor, has been shown to
delay the onset of diabetes in the NOD mouse model. However, the molecular
mechanism by which JANEX-1 protects pancreatic β-cells is unknown. In the ...
Cited by 1 - Related articles - All 3 versions

Expression of DBC1 and SIRT1 Is Associated with Poor Prognosis of Gastric Carcinoma


EJ Cha, SJ Noh, KS Kwon, CY Kim, BH Park, … - Clinical Cancer Research, 2009 - AACR
Results: Positive expressions of DBC1 and SIRT1 were seen in 62% (109 of 177)
and in 73% (130 of 177) of patients, respectively. Expression of DBC1 was
significantly correlated with tumor stage (P = 0.007), lymph node ...
Related articles - All 4 versions

Increases in nuclear p65 activation in dystrophic skeletal muscle are secondary to increases …


R Singh, G Millman, E Turin, L Polisiakeiwicz … - Journal of the Neurological Sciences, 2009 - Elsevier
Dystrophin-deficient muscle exhibits substantial increases in nuclear NF-κB
activation. To examine potential mechanisms for this enhanced activation, the
present study employs conventional Western blot techniques to provide the ...
Related articles - All 11 versions

A20 Attenuates Allergic Airway Inflammation in Mice


NI Kang, HY Yoon, YR Lee, M Won, MJ Chung … - The Journal of Immunology, 2009 - Am Assoc Immnol
TNF receptor 1 can activate signaling pathways leading to the activation of NF-
B. A20, an NF- B-inducible protein, negatively regulates these signaling
pathways and acts as an anti-inflammatory mediator. Therefore, A20 is ...
Cited by 1 - Related articles - All 3 versions

Histone Deacetylase Inhibitors Target Diabetes via Chromatin Remodeling or as Chemical …


MW Lawless, KJ OByrne, SG Gray - Current Diabetes Reviews, 2009 - ingentaconnect.com
Abstract: Globally, obesity and diabetes (particularly type 2 diabetes)
represents a major challenge to world health. De- spite decades of intense
research efforts, the genetic basis involved in diabetes pathogenesis & ...
Related articles - All 2 versions

Effects of caloric restriction on SIRT1 expression and apoptosis of islet beta cells in type 2 …


X Deng, J Cheng, Y Zhang, N Li, L Chen - Acta Diabetologica - Springer
Abstract Increasing evidence suggests that a restricted caloric intake extends
the life span of mammals, and SIRT1 may play a key role in this process. To
study the effects of caloric restriction on SIRT1 expression and apoptosis ...

Polymyxin B, scavenger of endotoxin, enhances isolation yield and in vivo function of islets


SG Park, JH Kim, JH Oh, HN Lee, HS Park, … - Transplant International, 2009 - interscience.wiley.com
Collagenase purified from bacteria has been used to isolate islets for
transplantation. However, collagenase is contaminated with small amounts of
endotoxin, which induces dysfunction or apoptosis of islets. In this study, ...
Related articles

Dihydroavenanthramide D protects pancreatic β-cells from cytokine and streptozotocin …


N Lv, MY Song, YR Lee, HN Choi, KB Kwon, … - Biochemical and Biophysical Research …, 2009 - Elsevier
Dihydroavenanthramide D (DHAvD) is a synthetic analog to naturally occurring
avenanthramide, which is the active component of oat. Although its
anti-inflammatory, antiatherosclerotic, and antioxidant effects have been ...
Related articles - All 3 versions

Metabolic benefits from Sirt1 and Sirt1 activators


N Chaudhary, PT Pfluger - Current Opinion in Clinical Nutrition & Metabolic Care, 2009 - journals.lww.com
Introduction Sirtuins, named after their homology to the Saccharomyces
cerevisiae gene silent information regulation-2 (Sir2), con- stitute a family of
highly conserved nicotinamide adenine dinucleotide (NADþ)-dependent ...
Cited by 1 - Related articles - All 3 versions


 


Go to Google Home - About Google - About Google Scholar

©2009 Google