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Scholar Results 1 - 4 of 4 citing Lindroos: m. 3243A> G Mutation in Mitochondrial DNA Leads to Decreased Insulin Sensitivity.... (0.06 sec) 

The Clinical Variability of Maternally Inherited Diabetes and Deafness Is Associated with …


M Laloi-Michelin, T Meas, C Ambonville, C … - Journal of Clinical Endocrinology & Metabolism, 2009 - Endocrine Soc
Results: A significant negative correlation was found between levels of
heteroplasmy and age of the patients at the time of sampling for molecular
analysis, age at the diagnosis of diabetes, and body mass index. After ...
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MITOCHONDRIAL DYSFUNCTION IN DIABETES: FROM MOLECULAR MECHANISMS TO …


WI Sivitz, MA Yorek - Antioxidants & Redox Signaling - liebertonline.com
Page 1. 1 COMPREHENSIVE INVITED REVIEW MITOCHONDRIAL DYSFUNCTION IN DIABETES: FROM
MOLECULAR MECHANISMS TO FUNCTIONAL SIGNIFICANCE AND THERAPEUTIC OPPORTUNITIES ...
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The Role of Mitochondria in the Pathophysiology of Skeletal Muscle Insulin Resistance


I Pagel-Langenickel, J Bao, L Pang, MN Sack - Endocrine Reviews, 2009 - Endocrine Soc
Multiple organs contribute to the development of peripheral insulin resistance,
with the major contributors being skeletal muscle, liver, and adipose tissue.
Because insulin resistance usually precedes the development of type 2 ...

Cerebral oxygen and glucose metabolism in patients with mitochondrial m. 3243A> G …


MM Lindroos, RJ Borra, R Parkkola, SM … - Brain, 2009 - Oxford Univ Press
The m.3243A>G mutation is the most common pathogenic mutation in mitochondrial
DNA. It leads to defective oxidative phosphorylation, decreased oxygen
consumption and increased glucose utilization and lactate production in ...
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