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Scholar Results 1 - 3 of 3 citing Sutherland: Interleukin-21 Is Required for the Development of Type 1 Diabetes in NOD Mice. (0.09 sec) 

Lymphocyte proliferation in immune-mediated diseases


S Datta, N Sarvetnick - Trends in Immunology, 2009 - Elsevier
Defects in T cell homeostatic mechanisms can result in T cell lymphopenia,
defined as decreased numbers of lymphocytes. Lymphopenia results in homeostatic
proliferation in order to maintain T cell homeostasis. It has been proposed ...
Cited by 1 - Related articles - All 4 versions

Interleukin-21 as a new therapeutic target for immune-mediated diseases


G Monteleone, F Pallone, TT Macdonald - Trends in Pharmacological Sciences, 2009 - Elsevier
Cytokines have a decisive role in initiating and shaping pathologic responses in
patients with various immune-inflammatory diseases. Recent studies indicate that
interleukin (IL)-21, a cytokine produced mostly by activated CD4+ T cells, ...
Related articles - All 2 versions

IL-21 is critical for GVHD in a mouse model


A Meguro, K Ozaki, I Oh, K Hatanaka, H … - Bone Marrow Transplantation, 2009 - nature.com
Immunological effects of IL-21 on T, B and natural killer (NK) cells have been
reported, but the role of IL-21 in GVHD remains obscure. Here, we demonstrate
that morbidity and mortality of GVHD was significantly reduced after BMT ...
Related articles - All 3 versions


 


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