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Scholar Results 1 - 10 of 10 citing Simon: Murine antithymocyte globulin therapy alters disease progression in NOD mice by a.... (0.16 sec) 

Human regulatory T cells: role in autoimmune disease and therapeutic opportunities


T Brusko, A Putnam, J Bluestone - Immunological Reviews, 2008 - interscience.wiley.com
SummaryThe importance of regulatory T lymphocytes (Tregs) in the control of
autoimmunity is now well established in a variety of experimental animal models.
In addition, there are numerous studies suggesting that Treg deficits may ...
Cited by 31 - Related articles - All 4 versions

Clinical application of regulatory T cells for treatment of type 1 diabetes and transplantation


T Brusko, J Bluestone - European Journal of Immunology, 2008 - interscience.wiley.com
Immune regulation is a complex process that depends on the maintenance of self
tolerance while retaining robust immune responses against microbes. The
emergence of Treg as a central mechanism for immune regulation has ...
Cited by 10 - Related articles - BL Direct - All 2 versions

Immunotherapy of type 1 diabetes


L Li, Z Yi, R Tisch, B Wang - Archivum Immunologiae et Therapiae Experimentalis, 2008 - Springer
Type 1 diabetes (T1D) is an autoimmune disease in which the insulin-producing β
cells are destroyed. Diabetic patients man- age their hyperglycemia by daily
insulin injections. However, insulin therapy is by no means a cure. ...
Cited by 3 - Related articles - All 4 versions

Parameters influencing antigen-specific immunotherapy for type 1 diabetes


B Wang, R Tisch - Immunologic research, 2008 - Springer
Abstract Type 1 diabetes (T1D) is a T cell-mediated autoimmune disease in which
the insulin producing b cells are destroyed. Antigen-based immunotherapy
provides an approach to selectively tolerize pathogenic b cell-specific T ...
Cited by 1 - Related articles - All 4 versions

Rabbit Polyclonal Mouse Antithymocyte Globulin Administration Alters Dendritic Cell …


Y Huang, M Parker, C Xia, R Peng, C … - The Journal of Immunology, 2009 - Am Assoc Immnol
Mouse antithymocyte globulin (mATG) prevents, as well as reverses, type 1
diabetes in NOD mice, through mechanisms involving modulation of the
immunoregulatory activities of T lymphocytes. Dendritic cells (DC) play a ...
Related articles - All 2 versions

[CITATION] In a mouse model thymoglobulin treatment results in depletion of naive as well as …


A Sener, AL Tang, DL Farber - American Journal of Transplantation, 2009 - Blackwell Publishing Inc
Related articles

[PDF] Immune Depletion with Cellular Mobilization Imparts Immunoregulation and Reverses …


MJ Parker, S Xue, JJ Alexander, CH … - Diabetes, 2009 - diabetes.ufl.edu
Page 1. ATG + G-CSF Reverses Overt Diabetes in NOD Mice Immune Depletion
with Cellular Mobilization Imparts Immunoregulation and ...
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In Vivo Characterization of Rabbit Anti-Mouse Thymocyte Globulin: A Surrogate for Rabbit …


MC Ruzek, KS Neff, M Luong, KA Smith, K … - Transplantation, 2009 - journals.lww.com
The T-cell depleting rabbit polyclonal antibody, anti- human thymocyte globulin
(Thymoglobulin), is currently in use for solid organ transplantation,
graft-versus-host disease (GVHD)in hematopoetic stem-cell transplantation, ...
Related articles - All 3 versions

Memory T-Cell Predominance Following T-Cell Depletional Therapy Derives from …


A Sener, AL Tang, DL Farber - American Journal of Transplantation, 2009 - pt.wkhealth.com
T-cell depletion reportedly leads to alterations in the T-cell compartment with
predominant survival of memory phenotype CD4 T cells. Here, we asked whether the
prevalence of memory T cells postdepletion results from their inherent ...
Related articles - All 4 versions

Targeted therapy to the IL-2R using diphtheria toxin and caspase-3 fusion proteins …


S Yarkoni, Y Sagiv, A Kaminitz, DL Farkas, N … - European journal of immunology, 2009 - interscience.wiley.com
Pathogenic lymphocytes in the enteric wall of inflammatory bowel disease
patients display various abnormalities, including reduced sensitivity to
apoptosis. We evaluated a therapeutic approach to elimination of cytotoxic ...
Related articles - All 3 versions


 


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