- ►diabetesjournals.org ZV Wang, J Mu, TD Schraw, L Gautron, JK … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—Islet transplantations have been performed clinically, but their
practical applications are limited. An extensive effort has been made toward the
identification of pancreatic β-cell stem cells that has yielded many ... Cited by 4 - Related articles - All 4 versions
- ►physiology.org S Pascal, Y Guiot, S Pelengaris, M Khan, JC … - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc Alteration of pancreatic β-cell survival and Preproinsulin gene expression by
prolonged hyperglycemia may result from increased c-MYC expression. However, it
is unclear whether c-MYC effects on β-cell function are compatible with ... Cited by 3 - Related articles - All 3 versions
M von Herrath, GT Nepom - Nature Immunology, 2009 - nature.com Type 1 diabetes is an immune-mediated disease in which pancreatic
insulin-producing beta cells are damaged and destroyed. Animal models have
served a prominent function in the development of the present ideas of ... Cited by 4 - Related articles - All 3 versions
T Jin - Medical hypotheses, 2008 - Elsevier Type II diabetes mellitus (T2D) develops as the consequence of relative insulin
insufficiency. The onset of T2D is characterized by insulin resistance, and in
most cases, with hyperinsulinemia for compensation. Extensive basic and ... Cited by 2 - Related articles - All 33 versions
MM Sachdeva, DA Stoffers - Molecular Endocrinology, 2009 - Endocrine Soc Type 2 diabetes results from pancreatic ß-cell failure in the setting of
insulin resistance. This model of disease progression has received recent
support from the results of genome-wide association studies that identify ... Cited by 2 - Related articles - All 3 versions
A Khalaileh, T Gonen-Gross, J Magenheim, T … - Diabetes, Obesity and Metabolism, 2008 - interscience.wiley.com Recent studies have revealed a surprising plasticity of pancreatic β-cell mass.
β-cell mass is now recognized to increase and decrease in response to
physiological demand, for example during pregnancy and in insulin-resistant ... Cited by 1 - Related articles - All 2 versions
S Efrat - The Review of Diabetic Studies: RDS, 2008 - pubmedcentral.nih.gov Ex-vivo generation of human insulin-producing cells is considered a promising
approach to providing an abundant source of cells for beta-cell replacement
therapy in diabetes. Expansion of adult beta-cells from the limited number ... Cited by 1 - Related articles - All 3 versions
HA Russ, P Ravassard, J Kerr-Conte, F Pattou, …, 2009 - pubmedcentral.nih.gov In-vitro expansion of functional beta cells from adult human islets is an
attractive approach for generating an abundant source of cells for beta-cell
replacement therapy of diabetes. Using genetic cell-lineage tracing we have ... Related articles - All 3 versions
DA Cano, M Hebrok - Gastroenterology, 2008 - theclinics.com No abstract is available. To read the body of this article, please view the Full
Text online. ... Corresponding Author Information Address requests for reprints
to: Matthias Hebrok, Diabetes Center, Department of Medicine, University of ... Related articles - Cached - All 21 versions
