JM Oliver-Krasinski, DA Stoffers - Genes & development, 2008 - genesdev.cshlp.org The major forms of diabetes are characterized by pancreatic islet β-cell dysfunction and decreased
β-cell numbers, raising hope for cell replacement therapy. Although human islet transplantation
is a cell-based therapy under clinical investigation for the treatment of type 1 diabetes, the ... Cited by 21 - Related articles - All 4 versions
B Hoffman, B Zavaglia, J Witzsche, TR de Algara … - Genome …, 2008 - genomebiology.com We used a specificity metric to identify 2,536 tags with pancreas-enriched expression compared
to 195 other mouse SAGE libraries. We subsequently grouped co-expressed transcripts with
differential expression during pancreas development using K-means clustering. We ... Cited by 3 - Related articles - Cached - All 7 versions
K Juhl, SA Sarkar, R Wong, J Jensen, JC Hutton - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—To document the transcriptome of the pancreatic islet during the early and late
development of the mouse pancreas and highlight the qualitative and quantitative features of
gene expression that contribute to the specification, growth, and differentiation of the ... Cited by 2 - Related articles - All 5 versions
IM Bochkis, J Schug, NE Rubins, AR … - Physiological …, 2009 - Am Physiological Soc Bile acids are powerful detergents produced by the liver to aid in the absorption of dietary
lipids. We recently reported a novel role for Foxa2 in bile acid metabolism. The winged helix
transcription factor Foxa2 is required to prevent intrahepatic cholestasis and liver injury in ... Related articles - All 3 versions
FC Lynn, L Sanchez, R Gomis, MS German, R Gasa - PLoS One, 2008 - pubmedcentral.nih.gov Basic helix-loop-helix (bHLH) transcription factors play important roles in differentiation processes
during embryonic development of vertebrates. In the pancreas, the atonal-related bHLH gene
Neurogenin3 (Neurog3) controls endocrine cell fate specification in uncommitted ... Related articles - All 6 versions
A Vetere, WC Li, F Paroni, K Juhl, L Guo, W Nishimura, … - Diabetologia - Springer Abstract Aims/hypothesis The basic helix–loop–helix transcription factor neurogenin-3
(NGN3) commits the fates of pancreatic progenitors to endocrine cell types, but knowledge of
the mechanisms regulating the choice between proliferation and differentiation of these ...
KK Leung, PM Suen, TK Lau, WH Ko, KM Yao … - Stem Cells and …, 2009 - liebertonline.com Page 1. 1 Revised Original Article to STEM CELLS AND DEVELOPMENT (ID#
SCD-2008-0325) PDZ-Domain Containing-2 (PDZD2) Drives the Maturity of Human Fetal
Pancreatic Progenitor-Derived Islet-Like Cell Clusters with Functional ... Related articles - All 3 versions
FX Jiang, M Mehta, G Morahan - Pancreas, 2009 - pdfs.journals.lww.com MATERIALS AND METHODS Bioinformatics Algorithms for Quantification of Insulin Gene Transcripts
During ISL Development Currently, the contrast of expression (M) calculated from normalized
microarray data sets has been used to quantify dif- ferential gene transcript ... Related articles - All 4 versions
S Rieck, P White, J Schug, AJ Fox, O Smirnova, … - Molecular …, 2009 - Endocrine Soc The inability of the ß-cell to meet the demand for insulin brought about by insulin resistance leads
to type 2 diabetes. In adults, ß-cell replication is one of the mechanisms thought to cause the
expansion of ß-cell mass. Efforts to treat diabetes require knowledge of the pathways that ... Related articles - All 3 versions
M Karaca, J Castel, C Tourrel-Cuzin, M Brun, A Géant … - 2009 - assets0.pubget.com Melis Karaca1*, Julien Castel1, Ce´cile Tourrel-Cuzin1, Manuel Brun2, Anne Ge´ant2, Mathilde
Dubois3, Sandra Catesson4, Marianne Rodriguez4, Serge Luquet1, Pierre Cattan5, Brian
Lockhart4, Jochen Lang3, Alain Ktorza2, Christophe Magnan1., Catherine Kargar2. 1 ... Related articles - View as HTML
