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Scholar Results 1 - 10 of 12 citing Gaulton: Comprehensive association study of type 2 diabetes and related quantitative traits.... (0.08 sec) 

An open access database of genome-wide association results


AD Johnson, CJ O'Donnell - BMC Medical Genetics, 2009 - ukpmc.ac.uk
The number of genome-wide association studies (GWAS) is growing rapidly leading to the discovery
and replication of many new disease loci. Combining results from multiple GWAS datasets may
potentially strengthen previous conclusions and suggest new disease loci, pathways or ...
Cited by 4

Emerging concepts in the pathophysiology of type 2 diabetes mellitus


PN Surampudi, J John-Kalarickal, VA Fonseca, … - Mt Sinai J …, 2009 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ...
Cited by 2 - Related articles - All 2 versions

Genes associated with risk of type 2 diabetes identified by a candidate-wide …

- diabetesjournals.org
SS Rich, JM Norris, JI Rotter - Diabetes, 2008 - Am Diabetes Assoc
Diabetes, and particularly type 2 diabetes, is one of the most significant public health problems
facing Western civilization. Every day, 4,100 people in the US are diagnosed with diabetes. Of
those with diabetes, each day, 230 have their legs amputated, 120 are newly placed on ...
Cited by 1 - Related articles - All 3 versions

RAPGEF1 gene variants associated with type 2 diabetes in the Korean population


KW Hong, HS Jin, JE Lim, HJ Ryu, MJ Go, JY Lee, … - Diabetes Research and …, 2009 - Elsevier
Under the activation of insulin receptors, glucose transporter 4 (Glut4) translocation is regulated
by two signal transduction pathways. These pathways are the PI 3-kinase-dependent pathway
and the CAP/TC10 pathway. The adaptor protein Rap guanine exchange factor 1 ( ...
Related articles - All 25 versions

Pathomechanisms of Type 2 Diabetes Genes

- spendocrinologia.org.pe [PDF] 
H Staiger, F Machicao, A Fritsche, HU Haring - Endocrine Reviews, 2009 - Endocrine Soc
Type 2 diabetes mellitus is a complex metabolic disease that is caused by insulin resistance
and β-cell dysfunction. Furthermore, type 2 diabetes has an evident genetic component and
represents a polygenic disease. During the last decade, considerable progress was ...
Related articles - All 4 versions

Direct and macrophage-mediated actions of fatty acids causing insulin resistance …


PJ Bilan, V Samokhvalov, A Koshkina, JD Schertzer, … - 2009 - Informa Pharma Science
Obesity is associated with insulin resistance and increased risk for developing type 2
diabetes. Enlarged adipocytes develop resistance to the anti-lipolytic action of insulin. Elevated
levels of fatty acids in the plasma and interstitial fluids lead to whole-body insulin ...
Related articles - All 5 versions

Characterization of Gene Interaction and Assessment of Ld Matrix Measures for the …

- duke.edu [PDF] 
DR Crosslin - dukespace.lib.duke.edu
Page 1. Characterization of Gene Interaction and Assessment of LD Matrix Measures for the
Analysis of Biological Pathway Association by David R. Crosslin Department of Computational
Biology & Bioinformatics Duke University Date: Approved: Dr. Terrence Furey, Supervisor ...
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Sorting Out Diabetes


CM Orme, JS Bogan - Science, 2009 - sciencemag.org
References 1. O. Hoegh-Guldberg et al., Science 318, 1737 (2007). 2. VM Weis, SK Davy, O.
Hoegh-Guldberg, M. Rodriguez- Lanetty, JR Pringle, Trends Ecol. Evol. 23, 369 (2008). 3. NH
Putnam et al., Science 317, 86 (2007). 4. MK Desalvo et al., Mol. Ecol. 17, 3952 (2008). 5. ...
Related articles - All 3 versions

Methods for Large-Scale Genetic Association Studies.

- umich.edu [PDF] 
KN Conneely - deepblue.lib.umich.edu
Methods for large-scale genetic association studies ... A dissertation submitted in partial fulfillment
of the requirements for the degree of Doctor of Philosophy (Biostatistics) in The University of
Michigan 2008 ... Professor Michael L. Boehnke, Chair Associate Professor Gonçalo ...
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Personal phenotypes to go with personal genomes


M Snyder, S Weissman, M Gerstein - Molecular Systems Biology, 2009 - pubmedcentral.nih.gov
With the cost of DNA sequencing decreasing rapidly, it is likely that the genome sequences of
many individuals will be determined. In fact, if half of the individuals in industrialized countries
choose to have their genomes sequenced, then well over 500 million personal genome ...
Cited by 1 - Related articles - All 4 versions


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