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Scholar Results 1 - 4 of 4 citing Jiang: Postnatal expansion of the pancreatic β-cell mass is dependent on survivin. (0.08 sec) 

Connective Tissue Growth Factor (CTGF) Inactivation Leads to Defects in Islet Cell …


LA Crawford, MA Guney, YA Oh, RA DeYoung, … - Molecular …, 2009 - Endocrine Soc
The factors necessary for normal pancreatic islet morphogenesis have not been well characterized.
Here we report that connective tissue growth factor (CTGF) is involved in the establishment of
normal islet endocrine cell ratio ...
Cited by 2 - Related articles - All 3 versions

Perinatal survivin is essential for the establishment of pancreatic beta cell mass in …


X Wu, L Wang, S Schroer, D Choi, P Chen, H Okada, M … - Diabetologia, 2009 - Springer
Abstract Aims/hypothesis Pancreatic beta cells undergo dynamic remodelling during the perinatal
period, with enhanced neogenesis, proliferation and apoptosis observed. The molecular mechanisms
responsible for these processes ...
Related articles - All 2 versions

β-cell death and proliferation after intermittent hypoxia: Role of oxidative stress


J Xu, YS Long, D Gozal, PN Epstein - Free Radical Biology and Medicine, 2009 - Elsevier
Intermittent hypoxia (IH), such as occurs in sleep apnea, induces increased oxidative stress and is
associated with altered glucose homeostasis. Because pancreatic β cells are very sensitive to
oxidative stress we tested whether ...
Cited by 1 - Related articles - All 2 versions

The transcriptional response of the islet to pregnancy in mice


S Rieck, P White, J Schug, AJ Fox, O Smirnova, … - Molecular …, 2009 - Endocrine Soc
The inability of the ß-cell to meet the demand for insulin brought about by insulin resistance
leads to type 2 diabetes. In adults, ß-cell replication is one of the mechanisms thought to cause
the expansion of ß-cell mass. ...
Related articles - All 3 versions


 


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