- ►nih.gov SM Raj, JMM Howson, NM Walker, JD Cooper, … - Diabetologia, 2009 - Springer Abstract Aims/hypothesis We used recently confirmed type 2 diabe- tes gene
regions to investigate the genetic relationship between type 1 and type 2
diabetes, in an average of 7,606 type 1 diabetic individuals and 8,218 ... Cited by 1 - Related articles - All 4 versions
L Egefjord, JL Jensen, CH Bang-Berthelsen, … - BMC Endocrine Disorders, 2009 - biomedcentral.com Our results showed a dynamic response of genes responsible for β-cell zinc
homeostasis to cytokines: IL-1β down regulated a number of zinc-transporters,
most strikingly ZnT8 in both islets and INS-1 cells. The effect was even ... Cited by 1 - Related articles - Cached - All 7 versions
J Jansen, W Karges, L Rink - The Journal of Nutritional Biochemistry, 2009 - Elsevier Zinc is an essential trace element crucial for the function of more than 300
enzymes and it is important for cellular processes like cell division and
apoptosis. Hence, the concentration of zinc in the human body is tightly ... Cited by 1 - Related articles - All 13 versions
KR Owen, MI McCarthy - Diabetologia, 2009 - Springer Page 1. COMMENTARY Type 1 and type 2 diabetes—chalk and cheese? KR Owen
& MI McCarthy Received: 17 May 2009 /Accepted: 10 July ... Related articles - All 2 versions
DA Chistiakov, NV Voronova - interscience.wiley.com Diabetes mellitus arises from defects in insulin secretion or action, or both.
In pancreatic islets, insulin production is linked with zinc transport mediated
by zinc transporter ZnT-8, a product of the SLC30A8 gene. Therefore, ... Related articles
DA Chistiakov, NV Voronova - BioFactors (Oxford, England) - ncbi.nlm.nih.gov Diabetes mellitus arises from defects in insulin secretion or action, or both.
In pancreatic islets, insulin production is linked with zinc transport mediated
by zinc transporter ZnT-8, a product of the SLC30A8 gene. Therefore, ... Related articles
PA Zalloua, ST Azar, M Delepine, NJ Makhoul … - Human Molecular Genetics, 2008 - Oxford Univ Press Most cases of juvenile-onset diabetes (JOD) are diagnosed as type 1 diabetes
(T1D), for which genetic studies conducted in outbred Caucasian populations
support the concept of multifactorial inheritance. However, this view may ... Related articles - All 4 versions
- ►diabetesjournals.org A Haupt, M Guthoff, B Gallwitz, HU Haring, A … - Diabetes Care, 2008 - Am Diabetes Assoc Genome-wide association studies have described new diabetes susceptibility genes
including TCF7L2, CDKAL1, HHEX, SLC30A8, CDKN2A/B, and IGF2BP2 (1). Most of
these novel risk loci are associated with impaired β-cell function (2). ... Related articles - All 4 versions
C Ionescu-Tîrgoviºte - Acta Endocrinologica (Buc), 2009 - 82.76.72.38 Abstract Based on epidemiological, clinic, biochemical and hormonal data (both
personal and international), our personal view is that natural history of
autoimmune type 1 diabetes could include the following stages: 1) The ... Related articles - View as HTML - All 2 versions
N Wijesekara, F Chimienti, MB Wheeler - Diabetes, Obesity and Metabolism, 2009 - interscience.wiley.com It is well known that zinc is required in pancreatic β-cells in the process of
insulin biosynthesis and the maturation of insulin secretory granules. In fact,
the zinc level in pancreatic islets is amongst the highest in the body and ... Related articles - All 2 versions
