C Hu, FS Wong, L Wen - Clin Exp Immunol, 2009 - interscience.wiley.com B cells play an important role in the pathogenesis of both systemic and organ-specific autoimmune
diseases. Autoreactive B cells not only produce autoantibodies, but are also specialized to efficiently
present specific autoantigens to T cells. Furthermore, these B cells can secrete pro- ... Cited by 2 - Related articles - All 3 versions
SK O'Neill, E Liu, JC Cambier - Current Opinion in Endocrinology, …, 2009 - journals.lww.com Introduction The failure to find a cure for type 1 diabetes has led to the exploration of efficacious
immunotherapies already approved for other diseases. A recent TrialNet study exploring the
use of rituximab in new onset type 1 dia- betics has been completed with positive ... Related articles - All 2 versions
SL Cox, PA Silveira - Expert Review of Clinical Immunology, 2009 - ingentaconnect.com Type 1 diabetes (T1D) is caused by immune infiltration of the pancreatic islets of Langerhans
(referred to as insulitis) followed by specific auto- immune-mediated destruction of the
insulin- secreting b-cells within them [1] . Predisposition to T1D depends on the ... Related articles - All 3 versions
PL Kendall, DJ Moore, C Hulbert, KL Hoek, … - The Journal of …, 2009 - Am Assoc Immnol Type 1 diabetes results from T cell-mediated destruction of insulin-producing ß cells. Although
elimination of B lymphocytes has proven successful at preventing disease, modulation of B cell
function as a means to prevent type 1 diabetes has not been investigated. The ... Related articles - All 3 versions
C Hu, FS Wong, L Wen - Clinical and Experimental Immunology, 2009 - pt.wkhealth.com B cells play an important role in the pathogenesis of both systemic and organ-specific autoimmune
diseases. Autoreactive B cells not only produce autoantibodies, but are also specialized to present
specific autoantigens efficiently to T cells. Furthermore, these B cells can secrete ...
HHM Abdu-Allah, K Watanabe, K Hayashizaki, Y … - Tetrahedron Letters, 2009 - Elsevier Synthetic ligands tagged with biotin have frequently been utilized to detect, localize, characterize
and recover the target protein. 4 Moreover, in order to pursue CD22 as a drug target, precise
and reproducible binding assays need to be developed. To address this goal we ... Related articles
- ►rexnealsmith.com [PDF] P Fiorina, M Jurewicz, A Augello, A Vergani, … - The Journal of …, 2009 - Am Assoc Immnol Human clinical trials in type 1 diabetes (T1D) patients using mesenchymal stem cells (MSC)
are presently underway without prior validation in a mouse model for the disease. In response
to this void, we characterized bone marrow-derived murine MSC for their ability to ... Related articles - All 5 versions