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Scholar Results 1 - 10 of about 208 citing LOEHRER: Cisplatin. (0.12 sec) 

Analysis of events associated with cell cycle arrest at G2 phase and cell death induced by …

- oxfordjournals.org [PDF] 
CM Sorenson, MA Barry, A Eastman - JNCI Journal of the National Cancer Institute, 1990 - jnci.oxfordjournals.org
DNA is the accepted target for cisplatin, but recent evidence has shed doubt on
DNA synthesis as the critical process. L1210/0 cells incubated for 2 hours with
cisplatin progress to the G 2 phase of the cell cycle and are arrested ...
Cited by 268 - Related articles - All 6 versions

Cellular and molecular determinants of cisplatin resistance


RP Perez - European Journal of Cancer, 1998 - Elsevier
Cisplatin and carboplatin are among the most active and widely used cytotoxic
anticancer drugs. However, the acquisition or presence of resistance
significantly undermines the curative potential of these drugs against many ...
Cited by 193 - Related articles - BL Direct - All 5 versions

Controlling delayed vomiting: double-blind, randomized trial comparing placebo, …

- jcojournal.org [PDF] 
MG Kris, RJ Gralla, LB Tyson, RA Clark, C … - Journal of Clinical Oncology, 1989 - jcojournal.org
DELAYED EMESIS is a distinct syndrome that occurs 24 or more hours following the
administration of the anticancer drug cisplatin.' In a prior study, delayed
vomiting occurred in 74% of patients and delayed nausea in 87% over a ...
Cited by 179 - Related articles - All 6 versions

Weekly gemcitabine with monthly cisplatin: effective chemotherapy for advanced non-small- …

- jcojournal.org [PDF] 
RP Abratt, WR Bezwoda, L Goedhals, DJ … - Journal of Clinical Oncology, 1997 - jcojournal.org
Purpose: The aim of this study was to examine the efficcyof a regimen of initial
gemcitabine followed by cisplatin in patients with advanced non-small-cell lung
cancer (NSCLC). Patients and Methods: Fifty-three patients (36 men and 17 ...
Cited by 176 - Related articles - BL Direct - All 6 versions

Increased gene-specific repair of cisplatin interstrand cross-links in cisplatin-resistant human …

- nih.gov [PDF] 
W Zhen, CJ Link Jr, PM O'connor, E Reed, R … - Molecular and Cellular Biology, 1992 - Am Soc Microbiol
Page 1. MOLECULAR AND CELLULAR BIOLOGY, Sept. 1992, p. 3689-3698 Vol. 12, No.
9 0270-7306/92/093689-10$02.00/0 Copyright © 1992, American ...
Cited by 139 - Related articles - All 5 versions

Cisplatin neurotoxicity: the relationship between dosage, time, and platinum concentration in …

- jcojournal.org [PDF] 
RW Gregg, JM Molepo, VJ Monpetit, NZ … - Journal of Clinical Oncology, 1992 - jcojournal.org
Purpose: To identify the major sites of platinum accu- mulation within neural
tissues after treatment with cispla- tin and to determine the relationship
between cumulative dosage, time, and the development of histopathological ...
Cited by 124 - Related articles - All 7 versions

Platinum-based anticancer agents: innovative design strategies and biological perspectives


YP Ho, SCF Au-Yeung, KKW To - Medicinal Research Reviews, 2003 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 110 - Related articles - BL Direct - All 4 versions

Metallothionein-mediated cisplatin resistance in human ovarian carcinoma cells


PA Andrews, MP Murphy, SB Howell - Cancer chemotherapy and pharmacology, 1987 - Springer
Summary. We have determined the ability of two human ovarian carcinoma cells to
over-express metallothioneins (MTs) and the subsequent effect this elevation has
on DDP cytotoxicity. Cells of 2008 and COLO 316 human ovarian carcinomas ...
Cited by 110 - Related articles - All 4 versions

Gemcitabine-a safety review


MS Aapro, C Martin, S Hatty - Anti-cancer drugs, 1998 - journals.lww.com
MS Aapro et al. greater when a 30 min infusion of gemcitabine is used. The
weekly and every other week schedule adminis- tered doses high enough to achieve
this. However, since responses were seen using the weekly schedule and ...
Cited by 95 - Related articles - BL Direct - All 4 versions

Etoposide, doxorubicin, and cisplatin chemotherapy for advanced gastric adenocarcinoma: …

- jcojournal.org [PDF] 
A Lerner, R Gonin, GD Steele Jr, RJ Mayer - Journal of Clinical Oncology, 1992 - jcojournal.org
Purpose: A phase II study of etoposide, doxorubicin, and cisplatin (EAP) therapy
in patients with advanced gastric carcinoma was performed in an attempt to con-
firm encouraging results reported by German investiga- tors using an ...
Cited by 98 - Related articles - All 7 versions


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