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Scholar Results 1 - 10 of about 614 citing BROWNLEE: Nonenzymatic glycosylation and the pathogenesis of diabetic complications. (0.10 sec) 

Advanced glycosylation products quench nitric oxide and mediate defective …

- nih.gov [PDF] 
R Bucala, KJ Tracey, A Cerami - Journal of Clinical Investigation, 1991 - pubmedcentral.nih.gov
Nitric oxide (an endothelium-derived relaxing factor) induces smooth muscle relaxation and is
an important mediator in the regulation of vascular tone. Advanced glycosylation end prod-
ucts, the glucose-derived moieties that form noncnzymatically and accumulate on ...
Cited by 765 - Related articles - All 6 versions

Glucose autoxidation and protein modification. The potential role of'autoxidative …

- nih.gov [PDF] 
SP Wolff, RT Dean - Biochemical journal, 1987 - pubmedcentral.nih.gov
Monosaccharide autoxidation (a transition metal-catalysed process that generates H202 and
ketoaldehydes) appears to contribute to protein modification by glucose in vitro. The metal-chelating
agent diethylenetriaminepenta-acetic acid (DETAPAC), which inhibits glucose ...
Cited by 716 - Related articles - All 5 versions

Diabetes mellitus and the risk of dementia: The Rotterdam Study


A Ott, RP Stolk, F Van Harskamp, HAP Pols, A Hofman, … - Neurology, 1999 - AAN Enterprises
All rights reserved. Print ISSN: 0028-3878. Online ISSN: 1526-632X. since 1951, it is now a weekly
with 48 issues per year. Copyright © 1999 by AAN Enterprises, Inc. ® is the official journal of
the American Academy of Neurology. Published continuously Neurology
Cited by 587 - Related articles - BL Direct - All 5 versions

Cachectin/TNF and IL-1 induced by glucose-modified proteins: role in normal …


H Vlassara, M Brownlee, KR Manogue, CA Dinarello, A … - Science, 1988 - sciencemag.org
Proteins undergo a series of nonenzymatic reactions with glucose over time to form advanced
glycosylation end products (AGEs). Macrophages have a receptor that recognizes the AGE moiety
and mediates the uptake and degradation of AGE proteins. This removal process is ...
Cited by 431 - Related articles - All 4 versions

Non–insulin-dependent diabetes mellitus and fasting glucose and insulin …

- ahajournals.org
V Salomaa, W Riley, JD Kark, C Nardo, AR Folsom - Circulation, 1995 - Am Heart Assoc
From the National Public Health Institute, Department of Epidemiology and Health
Promotion, Helsinki, Finland (VS); the Department of Neurology, Bowman Gray School of
Medicine, Winston-Salem, NC (WR); the Department of Social Medicine, Hadassah ...
Cited by 402 - Related articles - BL Direct - All 5 versions

Molecular understanding of hyperglycemia's adverse effects for diabetic …

- uoguelph.ca [PDF] 
MJ Sheetz, GL King - Jama, 2002 - Am Med Assoc
Diabetic complications are the major cause of morbidity and mortality in persons with
diabetes. Chronic hyperglycemia is a major initiator of diabetic microvascular complications
(eg, retinopathy, neuropathy, nephropathy). Glucose processing uses a variety of diverse ...
Cited by 378 - Related articles - BL Direct - All 6 versions

Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of …

- nih.gov [PDF] 
PJ Thornalley, A Langborg, HS Minhas - Biochemical Journal, 1999 - pubmedcentral.nih.gov
The glycation of proteins by glucose has been linked to the development of diabetic complications
and other diseases. Early glycation is thought to involve the reaction of glucose with N- terminal
and lysyl side chain amino groups to form Schiff's base and fructosamine adducts. The ...
Cited by 315 - Related articles - All 7 versions

Characterization of protein kinase C beta isoform activation on the gene …

- nih.gov [PDF] 
D Koya, MR Jirousek, YW Lin, H Ishii, K … - Journal of Clinical …, 1997 - pubmedcentral.nih.gov
J. Clin. Invest. © The American Society for Clinical Investigation, Inc. 0021-9738/97/07/0115/
12 $2.00 Volume 100, Number 1, July 1997, 115–126 ... Characterization of Protein Kinase
C Isoform Activation on the Gene Expression of Transforming Growth Factor- , ...
Cited by 302 - Related articles - All 9 versions

Association of diabetes mellitus and dementia: the Rotterdam Study


A Ott, RP Stolk, A Hofman, F Van Harskamp, DE … - Diabetologia, 1996 - Springer
Summary Dementia and non-insulin-dependent dia- betes mellitus (NIDDM) are highly prevalent
disor- ders in the elderly. Diabetes has repeatedly been re- ported to affect cognition, but its relation
with de- mentia is uncertain. We therefore studied the associa- tion between diabetes and ...
Cited by 291 - Related articles - BL Direct - All 3 versions

Advanced glycosylation: chemistry, biology, and implications for diabetes and …


R Bucala, A Cerami - Adv Pharmacol, 1992 - books.google.com
Advanced Glycosylation: Chemistry, Biology, and Implications for Diabetes and Aging Richard
Bucala and Anthony Cerami Laboratory of Medical Biochemistry The Rockefeller University New
York, New York 10021 I. Introduction II. Nonenzymatic Glycosylation A. Historical ...
Cited by 281 - Related articles - All 2 versions


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