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Scholar Results 1 - 10 of about 24 citing HENNESSEY: The equivalency of two L-thyroxine preparations. (0.09 sec) 

Bioequivalence of generic and brand-name levothyroxine products in the treatment …


BJ Dong, WW Hauck, JG Gambertoglio, L Gee, JR … - JaMa, 1997 - Am Med Assoc
OBJECTIVE: To compare relative bioavailability of Synthroid, Levoxine (Levoxine has been renamed
Levoxyl), and 2 generic levothyroxine sodium preparations. DESIGN: Single-blind (primary investigators
blinded), randomized, 4-way crossover trial. SETTING: Ambulatory care. PATIENTS: ...
Cited by 126 - Related articles - BL Direct - All 4 versions

Management practices among primary care physicians and thyroid specialists in …


MT McDermott, BR Haugen, DC Lezotte, S Seggelke, … - Thyroid, 2001 - liebertonline.com
Prospective studies are not available to address various issues commonly encountered in the
management of hypothyroid patients. We have conducted a case-based mail survey of American
Thyroid Association (ATA) members and primary care providers (PCP) regarding ...
Cited by 21 - Related articles - BL Direct - All 4 versions

Assessment of interchangeability of two brands of levothyroxine preparations with …


DA Escalante, N Arem, R Arem - The American journal of medicine, 1995 - Elsevier
Twenty-three of the 31 patients with long-standing primary hypothyroidism (6 men, 25
women; age range 30 to 71 years, mean 47.2 ± 2.2 SEM) were switched from Synthroid to Levoxine
(group 1) and the remaining patients from Levoxine to Synthroid (group 2). After ...
Cited by 15 - Related articles - All 6 versions

A study in normal human volunteers to compare the rate and extent of …


JA Berg, GH Mayor - The Journal of Clinical Pharmacology, 1992 - jclinpharm.highwire.org
Page 1. http://www.jclinpharm.org Pharmacology The Journal of Clinical 1992; 32; 1135 J. Clin.
Pharmacol. JA Berg and GH Mayor Synthroid and Levoxine A study in normal human volunteers
to compare the rate and extent of levothyroxine absorption from ...
Cited by 14 - Related articles - BL Direct - All 5 versions

Thyroid medications during pregnancy


TG Bach-Huynh, J Jonklaas - Therapeutic drug monitoring, 2006 - journals.lww.com
Euthyroid women experience dramatic changes in their thyroid physiology in order to accommodate
the presence of placental and fetal tissues. These adaptations to the pregnant state make it crucial
to develop reliable trimester-specific intervals for thyroid parameters. Use of non-pregnant ...
Cited by 12 - Related articles - BL Direct - All 5 versions

Levothyroxine a New Drug? Since When? How Could That Be?


JV Hennessey - Thyroid, 2003 - liebertonline.com
THE FOOD AND DRUG ADMINISTRATION (FDA) announced that orally administered drug products
containing levothyroxine sodium were new drugs on Thursday August 14, 1997 (1). My world
did not shake, quiver or turn upside down (but it should have). If I had been paying ...
Cited by 12 - Related articles - BL Direct - All 2 versions

Levothyroxine: therapeutic use and regulatory issues related to bioequivalence


L Wartofsky - eop, 2002 - informahealthcare.com
Levothyroxine is the overwhelming choice of clinicians for the treatment of hypothyroidism and
for the suppression of goitre and thyroid nodules in selected cases. The monitoring of serum
levels of thyroid stimulating hor- mone is necessary for appropriate dosage adjustment of ...
Cited by 11 - Related articles - All 4 versions

Altered bioavailability due to changes in the formulation of a commercial …


G Olveira, MC Almaraz, F Soriguer, MJ … - Clinical …, 1997 - interscience.wiley.com
We studied 58 patients with differentiated thyroid carcinoma (50 women and eight men; aged
22–75 years) who were being treated with levothyroxine and who had previously had adequate
TSH suppression. Their Levothroid® tablets were changed to the same dose of Dexnon® ...
Cited by 9 - Related articles - BL Direct - All 4 versions

Multiple level C in vitro/in vivo correlation of dissolution profiles of two l-thyroxine …


NM Volpato, RL Silva, APP Brito, JCS Gonçalves, M … - European journal of …, 2004 - Elsevier
In a previous study aimed to compare the bioavailability of two levothyroxine tablets, we found
a good relation between their pharmacokinetics parameters and dissolution profiles, employing
the USP dissolution conditions in use at that time (24th edition). Despite the formulations ...
Cited by 5 - Related articles - All 4 versions

Increase in plasma thyrotropin levels in hypothyroid patients during treatment due …

- endojournals.org
S Peran, MJ Garriga, G Morreale de Escobar, M … - Journal of Clinical …, 1997 - Endocrine Soc
Around mid-1995, the Molecular Endocrinology Laboratory of the Regional Hospital
(Malaga, Spain) began detecting an increase in TSH levels in the serum of patients under study
to control the treatment of hypothyroidism with levothyroxine. Over a period of 5 months, ...
Cited by 4 - Related articles - BL Direct - All 4 versions


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