- ►jcojournal.org [PDF] JM Kirkwood, MH Strawderman, MS Ernstoff, … - Journal of Clinical Oncology, 1996 - jcojournal.org Purpose: Interferon alfa-2b (IFNa-2b) exhibits antitu- mor activity in
metastatic melanoma and on this basis has been evaluated as an adjuvant therapy
following surgery for deep primary (T4) or regionally metastatic (N1) ... Cited by 1139 - Related articles - BL Direct - All 9 versions
I Gresser - Acta Oncologica, 1989 - informahealthcare.com Abstract Both natural and recombinant interferons have shown definite antitumor
activity in some patients with some malignancies. The history of the development
of interferon as an antitumor agent is reviewed, with special attention to ... Cited by 419 - Related articles - All 8 versions
- ►ascopubs.org [PDF] JR Quesada, M Talpaz, A Rios, R Kurzrock, … - Journal of Clinical Oncology, 1986 - jco.ascopubs.org A GREAT INTEREST in interferons (IFNs) in cancer treatment has gradually arisen
since partially purified human leukocyte IFN (IFNa) became available for
clinical investiga- tion.' 2 In the past 10 years, numerous biologic ... Cited by 409 - Related articles - All 6 versions
- ►pnas.org [PDF] JW Fountain, M Karayiorgou, MS Ernstoff, JM … - Proceedings of the National Academy of Sciences, 1992 - National Acad Sciences Page 1. Proc. Natl. Acad. Sci. USA Vol. 89, pp. 10557-10561, November 1992 Medical
Sciences Homozygous deletions within human chromosome band 9p2l in melanoma ... Cited by 226 - Related articles - BL Direct - All 8 versions
D Goldstein, J Laszlo - Cancer Res, 1986 - AACR Isaacs and Lindemann first characterized UN in England in 1957; they coined the
term to signify a protein elaborated by virally infected cells that functions to
prevent their infection by a second virus (1). However, difficulties with ... Cited by 141 - Related articles - All 3 versions
RC Cornell, HT Greenway, SB Tucker, L … - Journal of the American Academy of Dermatology, 1990 - Elsevier In a clinical trial of 172 patients at four medical centers, interferon alfa-2b
(1.5 × 10 6 IU) or a placebo was injected directly into biopsy-proved
noduloulcerative or superficial basal cell carcinomas three times weekly ... Cited by 123 - Related articles - All 2 versions
PI Ceballos, R Ruiz-Maldonado, MC Mihm - The New England journal of medicine, 1995 - nejm.highwire.org To give a child the ominous diagnosis of malignant melanoma is a very difficult
decision for both clinician and pathologist. Difficulties in histologic
diagnosis combined with a reluctance on the part of the clinician may lead ... Cited by 105 - Related articles - BL Direct - All 5 versions
- ►pnas.org HM Horton, D Anderson, P Hernandez, KM … - Proceedings of the National Academy of Sciences, 1999 - National Acad Sciences A cancer treatment is described in which im injection of plasmid DNA (pDNA)
encoding murine interferon α (mIFN-α) leads to potent antitumor effects on
primary and metastatic tumors in mice. Mice bearing sc B16F10 melanoma, ... Cited by 100 - Related articles - BL Direct - All 11 versions
GJ Mannering, LB Deloria - Annual review of pharmacology and toxicology, 1986 - Annual Reviews Early virologists observed that a patient or an experimental animal, once
recovered from a virus infection usually resisted reinfection from the same or
similar virus. Vaccination was one of the early applications of this phenom ... Cited by 81 - Related articles - All 4 versions
MD Peter Von Wussow, B Block, F Hartmann, … - CA A Cancer Journal for Clinicians - interscience.wiley.com Fifty-one evaluable patients with histologically proven metastatic melanoma and
at least one skin metastasis were treated intralesionally with interferon-alpha
(IFN- ). Twenty-six of the patients were given highly purified natural IFN- ... Cited by 70 - Related articles - All 3 versions
