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Scholar Results 1 - 10 of about 21 citing Hirsch: Prospects of therapy for infections with human T-lymphotropic virus type III. (0.09 sec) 

Treatment of Kaposi's sarcoma with interferon alfa-2b (Intron® A)


PA Volberding, RT Mitsuyasu, JP Golando, … - CA A Cancer Journal … - interscience.wiley.com
The activity of the alpha interferons against AIDS-related Kaposi's sarcoma (KS) has been demonstrated
in numerous clinical trials. Unfortunately, most reports have involved small patient cohorts and
a variety of dosages and schedules of administration. We report here a series of Phase II ...
Cited by 57 - Related articles - All 2 versions

[PDF] Inhibition of the reverse transcriptase from HIV by 3'-azido-3'-deoxythymidine …


L Vrang, H Bazin, G Remaud, J Chattopadhyaya, B … - Antiviral research, 1987 - boc.uu.se
3'-Azido-3'-deoxythymidine triphosphate (erythro) and its threo isomer were synthesized and
investigated for their inhibition of HIV reverse transcriptase from virus isolate U 937/HTLV-III.
The erythro isomer was a competitive inhibitor of the reaction directed by (rA)n(dT)12_18 ...
Cited by 45 - Related articles - View as HTML - All 4 versions

Cyclosporine-induced deterioration in patients with AIDS.

- nih.gov [PDF] 
A Phillips, MA Wainberg, R Coates, M … - CMAJ: Canadian …, 1989 - pubmedcentral.nih.gov
Eight patients with AIDS (acquired immune deficiency syndrome) but free of life-threatening infection
were treated with the immunosuppres- sive drug cyclosporine for a mean of 53.9 days. The serum
cyclosporine levels were maintained in the desired therapeutic range. All eight pa- tients ...
Cited by 41 - Related articles - All 10 versions

Biology and therapy of epidemic Kaposi's sarcoma


JE Groopman - CA A Cancer Journal for Clinicians - interscience.wiley.com
Kaposi's sarcoma, once a rarely seen neoplasm in the West, now occurs in an epidemic fashion
in association with acquired immune deficiency syndrome (AIDS). The pathogenesis of Kaposi's
sarcoma is still unclear but it appears to be an endothelial neoplasm. Its clinical ...
Cited by 26 - Related articles - All 2 versions

Trichosanthin treatment of HIV-induced immune dysregulation


RA Mayer, PA Sergios, K Coonan, LO'Brien - Eur. J. Clin. Invest, 1992 - interscience.wiley.com
Abstract. Twenty patients with the acquired immunodeficiency syndrome (AIDS), AIDS-related
complex (ARC) or asymptomatic HIV infection (HIV +) were given 20 meg kg -3 trichosanthin
(TCS; 'Compound Q'), a ribosome-inactivating protein with in vitro antiviral activity against ...
Cited by 23 - Related articles - All 4 versions

Different patterns of inhibition of avian myeloblastosis virus reverse transcriptase …

- nih.gov [PDF] 
B Eriksson, L Vrang, H Bazin, J … - Antimicrobial Agents …, 1987 - Am Soc Microbiol
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Apr. 1987, p. 600-604 0066-4804/87/040600
-05$02.00/0 Copyright © 1987, American Society for Microbiology ... Different Patterns of Inhibition
of Avian Myeloblastosis Virus ... Reverse Transcriptase Activity by 3'-Azido-3'- ...
Cited by 15 - Related articles - All 8 versions

Clinical Challenges of AIDS and HIV Infection, The


KH Mayer - L. Med. & Health Care, 1986 - heinonlinebackup.com
Researchers trying to resolve the questions surrounding the AIDS epidemic may feel like Hercules
trying to slay the Hydra: for every head that is cut off, two new ones grow in its place. Doctors
have never treated their pa- tients in a social vacuum, but the expectations and anx- ieties ...
Cited by 12 - Related articles - All 3 versions

In vitro suppression of HTLV-III/LAV infectivity by a combination of acyclovir and …


L Resnick, PD Markham, K Veren, SZ Salahuddin, … - The Journal of infectious …, 1986 - jstor.org
The discovery of HTLV-III/LAV (a cytopathic member of the human T lymphotropic retrovirus
[HTLV] family) and its identification as the etiologic agent of AIDS and its prodromes now permits
the consideration of therapy directed against this underlying causative agent [1,2]. Using ...
Cited by 11 - Related articles - All 3 versions

Vaccine and antiviral strategies against infections caused by human …

- nih.gov [PDF] 
MA Wainberg, O Kendall, N Gilmore - CMAJ: Canadian Medical …, 1988 - pubmedcentral.nih.gov
Human immunodeficiency virus type 1 (HIV-1) has been clearly associated with a variety of new
illnesses, including profound immunodefi- ciency (acquired immune deficiency syndrome
[AIDS]), wasting syndromes (formerly termed AIDS-related complex [ARC]) and ...
Cited by 8 - Related articles - All 10 versions

Effect of subcutaneous thymopentin treatment in drug addicts with persistent …

- nih.gov [PDF] 
W Barcellini, PL Meroni, D Frasca, C … - Clinical and …, 1987 - pubmedcentral.nih.gov
The effect of thymopentin treatmenton the immune defects in drugaddicts with persistent generalized
lymphadenopathy and HTLV-III infection was investigated. Thymopentin was administered subcutaneously
at two different dose schedules: 50 mg three times a week for 3 weeks (first cycle) and 50 ...
Cited by 9 - Related articles - All 4 versions


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