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Scholar Results 1 - 10 of about 54 citing TOPOL: Coronary thrombolysis with recombinant tissue-type plasminogen activator: a hematologic.... (0.09 sec) 

Hemorrhagic complications associated with the use of intravenous tissue plasminogen …


RM Califf, EJ Topol, BS George, JM Boswick, … - The American Journal of Medicine, 1988 - Elsevier
: Quantitation of blood loss during the patients' hospital stay included a
median drop in hematocrit of 11.4 points, a median nadir hematocrit of 31.2, a
14 percent rate of significant clinically evident bleeding, and a 31 ...
Cited by 84 - Related articles - All 4 versions

Increased plasma concentration of cross-linked fibrin polymers in acute myocardial …

- ahajournals.org [PDF] 
CW Francis, DG Connaghan, WL Scott, VJ … - Circulation, 1987 - Am Heart Assoc
THROMBOSIS is a pivotal event in the pathogenesis ofmyocardial infarction, with
a 70% to 90% incidence of acute thrombotic occlusion of the artery supplying the
infarcted zone in patients with transmural infarc- tions.' In addition, the ...
Cited by 66 - Related articles - All 4 versions

Intracranial hemorrhage after coronary thrombolysis with tissue plasminogen activator* 1


CS Kase, MS Pessin, JA Zivin, GJ del Zoppo, … - The American journal of medicine, 1992 - Elsevier
: Among 1,700 patients with an acute MI treated with an investigational
two-chain rtPA, duteplase (Burroughs Wellcome Co., Research Triangle Park, NC),
nine (0.53%) developed symptomatic ICH. Neurologic symptoms occurred ...
Cited by 63 - Related articles - All 5 versions

Thrombolysis with recombinant human tissue-type plasminogen activator in patients with …


RA Graor, B Risius, FV Lucas, JR Young, WF … - Circulation, 1986 - ncbi.nlm.nih.gov
Thirty-three patients with thrombosed peripheral arteries and bypass grafts, as
confirmed by angiography, were treated with recombinant human tissue-type
plasminogen activator (rt-PA). Twenty-six patients were treated with a dose ...
Cited by 59 - Related articles - All 4 versions

Recombinant human tissue-type plasminogen activator therapy in acute thromboembolic …


SM Papadopoulos, WF Chandler, MS Salamat, … - Journal of neurosurgery, 1987 - thejns.org
The authors designed a study to evaluate the effect of intravenous TPA
administered 2 hours after acute thromboembolic stroke in rats. This time course
was chosen to simulate an analogous clinical situation. Middle cerebral ...
Cited by 59 - Related articles - All 4 versions

Soluble fibrin degradation products potentiate tissue plasminogen activator-induced …

- nih.gov [PDF] 
JI Weitz, B Leslie, J Ginsberg - Journal of Clinical Investigation, 1991 - pubmedcentral.nih.gov
Despite its affinity for fibrin, tissue plasminogen activator(t- PA)
administration causes systemic fibrinogenolysis. To inves- tigate the mechanism,
t-PA was incubated with plasma in the presence or absence of a fibrin clot, ...
Cited by 45 - Related articles - All 6 versions

Pharmacodynamics of thrombolysis with recombinant tissue-type plasminogen activator. …

- ahajournals.org [PDF] 
DC Stump, RM Califf, EJ Topol, K Sigmon, D … - Circulation, 1989 - Am Heart Assoc
David C. Stump, MD, Robert M. Califf, MD, Eric J. Topol, MD, Kristina Sigmon,
MA, ... Dagnija Thornton, BS, Ramona Masek, RN, Linda Anderson, RN, ... Desire
Collen, MD, PhD, and the TAMI Study Group ... Coagulation analysis was ...
Cited by 46 - Related articles - All 6 versions

Human tissue-type plasminogen activator releases fibrinopeptides A and B from fibrinogen.

- nih.gov [PDF] 
JI Weitz, MK Cruickshank, B Thong, B Leslie, … - Journal of Clinical Investigation, 1988 - pubmedcentral.nih.gov
In five patients with venous thromboembolic disease treated with recombinant
tissue-type plasminogen activator (rt-PA), there was a marked increase in the
mean concentrations of fibrinopeptide A (from 0.6 to 5.9 nM; P < 0.0001) ...
Cited by 43 - Related articles - All 4 versions

Intracerebral hemorrhage complicating intravenous tissue plasminogen activator treatment


SE Carlson, MS Aldrich, HS Greenberg, EJ … - Archives of Neurology, 1988 - archneur.highwire.org
\s=b\ Tissue plasminogen activator's thrombolytic action is relatively specific
for fibrin; however, systemic bleeding can occur in patients, especially when
heparin is simultaneously administered. We de- scribe two cases of ...
Cited by 41 - Related articles - All 4 versions

Spontaneous splenic rupture complicating anticoagulant or thrombolytic therapy


JC Blankenship, M Indeck - The American journal of medicine, 1993 - Elsevier
7.L Norgren, B Eklof, JE Gjores, A Lohe and W Staszkiewicz, Spontan ruptur av
lever och mjälte vid streptokinasbehandling av djup ventrombos, Lakartidningen
75 (1978), pp. 777–778. ... 11.A ladicicco, R Manfrini, S Tabilio and CA ...
Cited by 33 - Related articles - BL Direct - All 4 versions


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